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Genetic and environmental modulators of neural encoding associated to speech processing and their relationship with auditory skills 

Puddu Gallardo, Giannina (Data de defensa: 2024-07-16)

[eng] Individuals exhibit variability in auditory processing skills, including those related to musical or speech perception, which rely on an accurate neural representation of the spectro-temporal characteristics of the ...

Cognitive decline in Mfn2 KO mice: role of Mfn2 in neuronal plasticity 

Riqué Pujol, Guillem (Data de defensa: 2025-04-11)

[eng] Mitofusin 2 (Mfn2) is a protein initially characterized as a mitochondrial fusion protein with a bioenergetic function, like Mitofusin 1. Beyond its role in bioenergetics, Mfn2 also acts as an ER-mitochondria tether, ...

Decoding Functional Genomics: Exploring Gene Expression Regulation and Unveiling the Drivers of Inter-Individual Variation 

Oliveros Diez, Winona (Data de defensa: 2025-04-07)

[eng] Understanding gene expression and its regulation is crucial for uncovering the molecular mechanisms driving phenotypic diversity and disease susceptibility. Regulatory regions of the genome, including non-coding ...

Identification of VAT1 as a regulator of lipid metabolism at mitochondria endoplasmic reticulum contact sites and implications in liver pathology 

Danezi, Aikaterini (Data de defensa: 2025-03-27)

[eng] Lipid homeostasis is of vital importance for cellular health and its disruption is a hallmark of disease. Recently, our lab reported that ablation of Mitofusin 2 (MFN2) leads to liver disease, a phenotype driven by ...

In utero green space exposure, DNA methylation, and birth size metrics 

Aguilar Lacasaña, Sofía (Data de defensa: 2025-03-24)

[eng] An increasing body of evidence has established health benefits of exposure to green space. Notably, in utero exposure to green space has been linked to a reduced risk of adverse birth outcomes, such as low birth ...

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