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Uncovering novel biomarkers for Parkinson’s disease and its prodromal stages
[eng] Parkinson’s disease (PD) is the most common neurodegenerative movement disorder characterised by loss of dopaminergic neurons and the accumulation of aggregated α-synuclein. Clinical diagnosis is based on the appearance ...
Característiques distintives del Test de Latències de Son Múltiples (MSLT) en la narcolèpsia
[cat] Aquesta Tesi Doctoral es presenta en format compendi d’articles, que corresponen a la mateixa unitat temàtica: l’estudi de trets distintius de la narcolèpsia en el Test de Latències de Son Múltiples (MSLT). En aquesta ...
Structural Genomic Alterations in Hepatocellular Carcinoma and Novel Combination Therapies
[eng] INTRODUCTION: Primary liver cancer is the sixth most diagnosed cancer and the second leading cause of cancer-related death worldwide. Around 90% of cases correspond to hepatocellular carcinoma (HCC), which normally ...
Development and application of computational methodologies for novel therapeutic strategies based on protein-protein interactions
[eng] Protein-protein interactions (PPIs) are essential for the proper functioning of biological systems, regulating key cellular processes such as protein degradation, signaling, and immune responses. This makes them both ...
Sujeto, experiencia y lenguaje: notas para una interpretación
[spa] La tesis piensa la zona de ruptura o crisis en la vida de los sujetos. El primer tramo de su recorrido intenta el desplazamiento desde un gesto hermenéutico de aprehensión, según modelos explicativos imperantes a un ...
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