Cánovas Bilbao, Begoña (Date of defense: 2017-07-20)
In normal epithelial cells, p38α has a well-established role as a tumor suppressor. However, recent reports have illustrated pro-tumorigenic functions for the p38α pathway by promoting tumor cell survival ...
Román González, Lidia (Date of defense: 2014-01-31)
Within the hematopoietic system, all mature blood cells are generated. Every differentiation step is characterized by the activation of a new, lineage specific, genetic program and the extinction of the ...
Recalde-Percaz, Leire (Date of defense: 2021-06-30)
Metastases are considered the last stage of tumour progression and the main cause of death associated to solid tumours. There are no effective treatments for metastasis which remain non- curable with ...
Bassani, Nicklas (Date of defense: 2017-12-15)
Antiangiogenic drugs are used clinically for treatment of different types of cancers and in the case of renal cell carcinoma (RCC) are now standard first-line treatments (Rini, 2009). Nevertheless, these ...
Urruticoechea Ribate, Ander (Date of defense: 2008-01-29)
DE LA TESIS:<br/><br/>El cáncer primario de mama es un problema de salud de gran magnitud con una incidencia estimada de 1 de cada 10 mujeres. De entre los tratamientos sistémicos, el tratamiento hormonal ...
Nicolàs Pàrraga, Sara (Date of defense: 2018-11-05)
Low risk Human Papillomaviruses (LR-HPVs) 6 and 11 are the main causative agents of benign proliferative lesions such genital warts (GWs) and recurrent respiratory papillomatosis (RRP) (Aubin et al. ...
Riera-Punet, Nina (Date of defense: 2019-03-01)
INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by progressive degeneration of the lower (LMN) and upper motor neurons (UMN) in the spinal cord and brain, ...
Casulleras i Oliver, Mireia (Date of defense: 2022-07-15)
[eng] This doctoral thesis is divided in two studies with the commune aim of elucidating the molecular mechanisms of albumin on leukocytes, in the context of advanced liver cirrhosis. The first study ...
Vidal Crespo, Anna (Date of defense: 2017-04-28)
In this thesis we have focused on two novel therapeutic strategies that target the crosstalk between the tumor cells and the microenvironment. Chronic lymphocytic leukemia (CLL) remains an incurable ...
López Solá, Marina (Date of defense: 2010-07-20)
The PhD thesis aimed to characterize the dynamic or temporal dimension of the emotional experience assessed using functional magnetic resonance imaging (fMRI). Brain response to primary emotional stimuli ...