López Asamar, Abraham (Date of defense: 2015-07-17)
Prolyl oligopeptidase (POP) is an 81-KDa bidomain enzyme which hydrolyses short proline-containing peptides. This enzyme is involved in mnemonic and cognitive processes, and the dysregulation of POP ...
Bertran Junqué, Alexandra (Date of defense: 2018-10-25)
Matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases involved in the degradation of the extracellular matrix. They make a major contribution to the progression of a vast number ...
Mendieta Martínez, Laura (Date of defense: 2014-06-06)
Proteases are involved in a high number of diseases, and thus, are relevant targets. For that reason our main goal was the discovery of protease inhibitors as therapeutic agents. We focused our study ...
Sabidó Aguadé, Eduard (Date of defense: 2008-11-24)
Actualment, les proteïnes implicades en la biosíntesi i la degradació dels neuropéptidos estan cobrant un gran interès com a possibles noves dianes terapèutiques ja que determinen els nivells de neuropèptid ...