Now showing items 138-143 of 143

    Tautomería de valencia en moléculas con número par de electrones: transición térmica al estado electrónico triplete inducida por un cambio conformacional. Nuevos materiales con comportamientos ferromagnéticos 

    Heras, Carlos, 1986- (Date of defense: 2016-01-18)

    Se han sintetizado una nueva familia de moléculas, puramente orgánicas y con número par de electrones, que presentan propiedades paramagnéticas. El trabajo de esta tesis ha consistido en conocer el fundamento por el cual ...

    The dynamic nature of amyloid-beta protein aggregation and its association to Alzheimer’s disease 

    Vilaprinyó Pascual, Sílvia (Date of defense: 2015-07-27)

    Amyloid-beta protein (Aß) is strongly linked to the aetiology of Alzheimer’s disease (AD). Even though Aß has a central role in AD, this protein is normally produced in healthy humans. It is the aberrant processing of Aß ...

    The synthesis and application of bulky S-stereogenic and P- stereogenic chiral ligands 

    Doran, Seán (Date of defense: 2012-12-14)

    This doctoral thesis was focused on the design and synthesis of novel chiral ligands for application in asymmetric catalysis. One of the best examples of asymmetric catalysis is the asymmetric hydrogenation reaction for ...

    Thiopeptides: Synthesis and Structure-Activity Relationship Studies 

    Just Baringo, Xavier (Date of defense: 2013-11-25)

    The present doctoral thesis has been devoted to the development of a new synthetic strategy to obtain a new member of the thiopeptide, or thiazolyl peptide, family of antibiotics. This new member, baringolin, was isolated ...

    Universal diagnostic platforms based on oligonucleotide codified nanoparticles and DNA microarray devices 

    Broto Avilés, Marta (Date of defense: 2017-09-18)

    La medicina personalitzada esta prenent rellevància últimament. Aquesta es basa en la monitorització simultània de diferents biomarcadors, els biomarcadors poden ser molècules de diferent naturalesa química. Aquest fet fa ...

    Use of calix[4]arenes to recover the self-assembly ability of mutated p53 tetramerization domains 

    Gordo Villoslada, Susana (Date of defense: 2008-06-30)

    Protein-protein interactions are essential in biological processes and thus, they have become very promising therapeutic targets. Nevertheless, the artificial modulation of protein complexes remains a challenge. Since most ...