Search

Now showing items 1-3 of 3

A human pancreatic ribonuclease variant kills cancer cells by apoptosis and reduces the expression of P-glycoprotein in MDR cell lines

Castro Gallegos, Jessica (Date of defense: 2010-10-26)

En aquesta tesi s'han estudiat les propietats antitumorals d'una variant de la ribonucleasa pancreàtica humana anomenada PE5 que incorpora un senyal de localització nuclear. Aquest estudi mostra que PE5 ...

Characterization of cytotoxic ribonucleases: from the internalization pathway to the importance of dimeric structures

Rodríguez Maynou, Montserrat (Date of defense: 2006-12-15)

En aquesta tesi s'ha caracteritzat la ruta d'internalització de l'onconasa, una RNasa citotòxica. Els resultats indiquen que l'onconasa entra a les cèl·lules per la via dependent de clatrina i del complex ...

Molecular mechanism of PE5-induced cytotoxicity and generation of new cytotoxic nuclear-directed

Vert Company, Anna (Date of defense: 2014-07-30)

Cytotoxic ribonucleases are promising agents to be used in the treatment of cancer. Our group previously described a cytotoxic human pancreatic ribonuclease variant, named PE5, which carries a nuclear ...

Search

A human pancreatic ribonuclease variant kills cancer cells by apoptosis and reduces the expression of P-glycoprotein in MDR cell lines

Characterization of cytotoxic ribonucleases: from the internalization pathway to the importance of dimeric structures

Molecular mechanism of PE5-induced cytotoxicity and generation of new cytotoxic nuclear-directed

Filter

Director

Date of defense

Language

Keywords and Knowledge Area

Subjects

Full text availability

Search

Filters

A human pancreatic ribonuclease variant kills cancer cells by apoptosis and reduces the expression of P-glycoprotein in MDR cell lines

Characterization of cytotoxic ribonucleases: from the internalization pathway to the importance of dimeric structures

Molecular mechanism of PE5-induced cytotoxicity and generation of new cytotoxic nuclear-directed