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  2. Universitat de Girona
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Universitat de Girona

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Estudi de l'acció de diferents bloquejadors de la via ErbB en la teràpia antitumoral 

Ferrer Soler, Laura (Date of defense: 2007-03-30)

L'inhibidor de carboxipeptidasa de patata (PCI) és un antagonista de l'EGF. Un dels problemes del PCI, però, és la baixa afinitat per l'EGFR en comparació amb el lligand natural. En aquest treball s'han ...

Role of alpha 2,3-sialyltransferases ST3Gal III and ST3Gal IV in pancreatic ductal adenocarcinoma 

Pérez Garay, Marta (Date of defense: 2011-02-07)

Este trabajo demuestra que los genes que codifican para los enzimas beta-galactosido alfa-2,3-sialiltransferasa 3 (ST3Gal III), y en menor medida beta-galactosido alfa-2,3-sialiltransferasa 4 (ST3Gal ...

Estudi de l'activitat antitumoral de nous compostos basats en metalls de transició 

González Bártulos, Marta (Date of defense: 2017-03-17)

Nowadays, cancer is one of the leading causes of death in developed countries. Therefore, there is great interest of developing new therapeutic strategies to improve the efficiency of current cancer ...

Regulation and function of silayltransferases in pancreatic cancer 

Bassagañas i Puigdemont, Sònia (Date of defense: 2014-12-03)

Changes in the expression of Lewis-type glycan antigens, especially a predominance of sialyl-Lewis x (SLex) structure, and the glycosyltransferases involved in its synthesis, correlate with pancreatic ...

Antitumoral properties of epidermal growth factor derivatives 

Panosa Roqueta, Clara (Date of defense: 2015-12-14)

The members of the epidermal growth factor (EGF) / ErbB family are prime targets for cancer therapy. However, the therapeutic efficiency of the existing anti-ErbB agents is limited. Thus, identifying ...

Nous mecanismes de resistència primària al trastuzumab (Herceptin): bases moleculars per a la determinació d'un nou subtipus de càncer de mama (Basal/ErbB2+) 

Oliveras Ferrarós, Cristina (Date of defense: 2013-06-21)

The aim of this doctoral thesis was to unravel mechanisms underlying primary resistance to trastuzumab regarding a putative new breast cancer subtype with mixed basal & ErbB2+ molecular features. Using ...

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Peracaula Miró, Rosa (2)

Llorens Duran, Rafael de (1)

Massaguer i Vall-llovera, Anna (1)

Menéndez Menéndez, Javier Abel (1)

Ribas Salamaña, Xavi (1)

Date of defense

2010 - 2017 (5)

2007 - 2009 (1)

Language

English (4)

Catalan (3)

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Keywords and Knowledge Area

Cancer (6)

Càncer (3)

Cáncer (3)

Cèl·lules mare (2)

Células madre (2)

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Subjects

577 - Material bases of life. Biochemistry. Molecular biology. Biophysics (6)

616 - Pathology. Clinical medicine (4)

576 - Cellular and subcellular biology. Cytology (2)

... Show more

Full text availability

Open access (6)

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