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Estudi de la reacció de trans-splicing i caracterització fisicoquímica de la inteïna partida Neq DNA polimerasa B de l'hipertermòfil N. equitans

Gordo Hernández, Verónica (Date of defense: 2021-06-23)

Protein splicing is an autocatalytic process with different stages that involves the elimination of an internal sequence, called intein, from the precursor polypeptide chain and the formation of a ...

Structural and functional characterization of Apoptin and design of a monomeric variant with antitumor activity

Ruiz Martínez, Santiago (Date of defense: 2016-07-08)

The main aim of the present study is to characterize the biological and biophysical properties of Apoptin, a viral protein that selectively induces apoptosis of a wide range of tumor cells. Apoptin has ...