Synthesis of TGF-Beta inhibitors and compounds for spatiotemporal drug release 

Byrom, Daniel (Date of defense: 2018-11-23)

During this doctoral thesis, we have synthesised hundreds of grams of the TGF-β inhibitor LY2157299 (Galunisertib). This product was used by the group of Eduard Batlle in their investigations into the roles that TGF-β plays ...