A bioengineering approach for corneal endothelial regeneration. 

    Bosch Canals, Begoña María (Date of defense: 2019-07-16)

    Nowadays, there are approximately 10 million people worldwide with visual impairment due to corneal diseases. Currently, the main therapeutic solution is the transplant of a donor's cornea. The great majority of transplants ...

    CDK-mediated phosphorylation of Yku80 and its role in DNA repair 

    Carballar Ruiz, María de los Reyes (Date of defense: 2021-02-25)

    DNA double-strand breaks (DSBs) are considered the most deleterious lesions of DNA and they are repaired by means of two main mechanisms: homologous recombination (HR) and non-homologous endjoining (NHEJ). These mechanisms ...

    Development of novel bioinks formulations based on supramolecular self-assembled hydrogels for tissue regeneration. 

    Merino Gómez, María (Date of defense: 2023-04-21)

    The field of tissue engineering relies on the use of biomaterials as scaffolds for tissue and organ regeneration. If properly designed, these scaffolds can mimic the in vivo microenvironment while also providing initial ...

    Development of sol-gel silica-based 3D printable materials with tunable degradation, mechanical properties and drug release capacity for tissue engineering 

    Rodríguez González, Raquel (Date of defense: 2023-02-07)

    The bone is a very complex organ that participates in multiple critical functions for the human body. Bone can be affected by different health issues, such as physical trauma or tumor, and the body cannot regenerate large ...

    Evaluation of biomarkers for studying new challenges in tobacco control 

    Pérez - Martín, Hipólito (Date of defense: 2023-11-17)

    El tabaquismo es reconocido a nivel global como un factor de riesgo significativo para la salud pública y una de las principales causas de muertes prevenibles. España ha implementado políticas de control del tabaco con el ...

    Iron Regulatory Protein/Iron Responsive Element (IRP/IRE) system: associated diseases and new target mRNAs (PPP1R1B) 

    Celma Nos, Ferran (Date of defense: 2022-05-17)

    Iron is a biometal involved in many physiological processes essential for life. Regulation of both systemic and cellular iron homeostasis is crucial for health. The IRP/IRE post-transcriptional regulatory system is in ...

    Localización del foramen mandibular: estudio anatómico mediante tomografía computarizada (TC) 

    Parellada Insa, Héctor (Date of defense: 2012-07-16)

    Para la mayoría de tratamientos dentales, es efectiva la utilización de técnicas anestésicas de tipo infiltrativo, consiguiendo el bloqueo efectivo del estímulo doloroso en todos los dientes de la arcada superior y del ...

    Modulation of the inflammatory response using a guided bone regeneration membrane with dual drug delivery capacity 

    Díez Tercero, Leire (Date of defense: 2021-06-08)

    Bone is a complex and dynamic tissue that fulfills several critical functions such as protecting vital organs including the brain, heart and lungs; providing sites of attachment for muscles to allow movement and maintaining ...

    Obtaining hepatocyte-like cells from dental pulp pluripotent-like stem cells 

    Gil Recio, Carlos (Date of defense: 2015-06-29)

    The liver is the largest internal organ and an important regulator of homeostasis providing essential metabolic, exocrine and endocrine functions. Liver diseases result in high rates of morbidity and mortality and affect ...