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CDK-mediated phosphorylation of Yku80 and its role in DNA repair

Carballar Ruiz, María de los Reyes (Date of defense: 2021-02-25)

DNA double-strand breaks (DSBs) are considered the most deleterious lesions of DNA and they are repaired by means of two main mechanisms: homologous recombination (HR) and non-homologous endjoining ...

CPT1c in specific hypothalamic nuclei and its role in lipid sensing and metabolic adaptation

Fosch Masllovet, Anna (Date of defense: 2022-07-28)

Obesity has become a pandemic disease in the last 40 years. The WHO estimates that the population with overweight has nearly tripled since 1975, and the tendency is still growing. These data have an ...