Browsing by Title

Study of new propargylamine and donepezil-derived compounds as multitarget agents for the treatment of alzheimer’s disease

Bolea Tomás, Irene (Date of defense: 2011-07-27)

El compuesto PF9601N es un derivado de propargilamina y un potente inhibidor irreversible de la enzima monoamino oxidasa B (IMAO-B) el cual fue identificado por nuestro grupo tras una extensiva búsqueda de potenciales ...

Study of nutritional strategies to improve rearing, quarantine, and adaptation periods of replacement gilts

Fabà Camats, Lluís (Date of defense: 2019-01-24)

En la present tesi, es varen hipnotitzar reduccions en coixeses, osteocondrosis (OC) i lesions de peülles via proporcionar una suplementació dietètica (de nutrients importants en ossos i peülles) i/o reduir el creixement ...

Study of Organic Semiconductors for Device Applications

Stella, Marco (Date of defense: 2010-03-12)

Organic semiconductors are being investigated as an alternative to more traditional materials such as silicon, for the fabrication of different types of electronic devices. The advantages of such materials are flexibility, ...

Study of potential alternatives to human digestive enzymes and prediction of digestibility and bioaccessibility of starch containing meals

Payeras Perelló, Francina Maria (Date of defense: 2023-07-12)

[eng] This PhD thesis investigates the adaptation of two in vitro digestion methods for glycaemic index prediction and also outlines the effect of the macronutrients on the digestion of two starch sources. Potential ...

Study of pro-apoptotic protein RTP801 homeostasis and its regulation by NEDD4 in Parkinson's disease

Canal de la Iglesia, Mercè (Date of defense: 2016-06-01)

Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons of the Substantia Nigra pars compacta (SNpc) and the presence of cytoplasmic protein inclusions named Lewy Bodies. Current treatments are directed ...

Study of radiative decays at LHCb and search for the Λb0->pπ-γ decay

Alfonso Albero, Alejandro (Date of defense: 2022-02-11)

The main goal of this thesis is to study the radiative decays produced in one of the four big detectors of LHC, LHCb, which focuses on the study of matter-antimatter asymmetry through b and c quarks. In particular, the ...

Study of radiotherapy resistance associated to EGFR/MAPK signaling pathway and its application in the rational design of a treatment with simvastatin in combination with cetuximab and radiotherapy (in experimental models of carcinoma)

Llobet Cucalón, Lara Isabel de (Date of defense: 2013-11-22)

1. Generation and characterization of a radioresistant cell line In the first part of this project of Thesis, we subjected culture cells to fractionated radiation and clonal selection, to obtain a modified cohort of ...

Study of RBC shape transitions induced by nanoparticles

Carneiro Dias, André Eduardo (Date of defense: 2019-07-08)

Aquesta tesi descriu l'estudi de les propietats del medi extracel·lular sobre la criopreservació de glòbuls vermells i la possible aplicació de nanopartícules de sílice com a co-agents per al lliurament intracel·lular de ...

Study of reactive oxygen species (ROS) and nitric oxide (NO) as molecular mediators of the sepsis-induced diaphragmatic contractile dysfunction : protective effect of heme oxygenases

Barreiro Portela, Esther (Date of defense: 2002-06-18)

Protein nitration is considered as a marker of reactive nitrogen species formation. Heme oxygenases (HOs) are important for the defence against oxidative stress. We evaluated the involvement of the neuronal (nNOS), the ...

Study of reactive oxygen species-induced ion transport in different models by using electrophysiological approaches.

Rodrigo Moreno, Ana (Date of defense: 2012-04-27)

En esta tesis doctoral se analiza el papel del estrés oxidativo en el transporte iónico en distintos modelos, mediante técnicas de imagen y de electrofisiología. El trabajo se subdivide en cuatro capítulos. El primero, ...

Study of related senescence pathways in soft tissue tumors development

Simonetti, Sara (Date of defense: 2017-04-21)

Introducción: En esta tesis doctoral hemos estudiado y analizado los marcadores de senescencia celular en un subgrupo de tumores de partes blandas, los tumores de la vaina nerviosa periférica (PNSTs), neoplasias que pueden ...

Study of relaxation phenomena and local structure evolution in metallic glasses by means of Mössbauer and mechanical spectroscopy

Panahi, Seyedeh Leila (Date of defense: 2023-05-08)

(English) New research shows that global demand for alloys with unique properties for various applications increased drastically, and among all them the demand for high entropy and metallic glasses in the industry is ...

Study of relevant factors in the treatment of effluents by fungi for the degradation of emerging contaminants

Badia Fabregat, Marina (Date of defense: 2014-12-05)

Els contaminants emergents són un ampli grup de compostos orgànics detectats en diversos compartiments ambientals. Tot i que la seva concentració normalment està compresa entre els ng/L fins a pocs µg/L (força inferior que ...

Study of salinity retrieval errors for the SMOS mission

Gabarró Prats, Carolina (Date of defense: 2004-12-17)

El treball realitzat en aquesta tesi està emmarcat en la missió SMOS (Soil Moisture and Ocean Salinity) de l'Agència Espacial Europea. El satèl·lit es llançarà al febrer del 2007, i mesurarà la salinitat superficial del ...

Study of Se-biofortified functional food: Interactions and competing mechanisms among different elements using synchrotron analytical techniques

Manivannan, Nithyapriya (Date of defense: 2021-11-09)

El seleni (Se) és un dels micronutrients essencials per a un adequat metabolisme dels éssers humans. Les espècies de Es i la seva concentració tenen un paper clau en la seva biodisponibilitat. El S’és incorporat en el cos ...

Study of serum levels of insulin-like growth factor -1, insulin - like growth factor bunding protein -1 and -3, prealbumin and aminoterminal propetide of type -1 procollagen in infants and children with protein energy malnutrition

Alatrouni, Almahdi Mohamed (Date of defense: 2004-11-15)

Protein energy malnutrition (PEM) is a range of pathological conditions arising from coincident deficiency of proteins and calories in varying proportions occurring mostly in infants and young children. <br/>According to ...

Study of similarities and differences between circulating hepatitis B virus RNA and DNA quasispecies in different regions of viral genome and development of an antiviral gene therapy strategy

García García, Selene (Date of defense: 2023-06-06)

Al 2019, la Organització Mundial de la Salut (OMS) va estimar que 296 milions de persones a tot el món vivia amb infecció crònica pel virus de la hepatitis B (VHB), amb 1,5 milions de noves infeccions per any malgrat la ...

Study of social behavior through mixed methodology in the context of a social-skills program for children and adolescents with autism spectrum disorder in a community setting

Alcover Van de Walle, Carlota (Date of defense: 2021-06-30)

Al llarg de l'última dècada s'han realitzat s'han realitzat nombrosos estudis per avaluar l'eficàcia dels grups d'intervenció en habilitats socials per a persones amb trastorn de l'espectre autista (TEA). Segueix existint ...

The study of social egg freezing applying theories of framing and social domains: from the communicative treatment to the perception

Mohammadi, Leila (Date of defense: 2019-09-16)

L'objectiu general d'aquest estudi és explorar el tractament comunicatiu que les clíniques de fertilitat fan servir als seus llocs web per oferir tractaments de congelació d'òvuls per raons socials i entendre les percepcions ...

Study of solid particle materials as high temperature Thermal Energy Storage and Heat Transfer Fluid for Concentrating Solar Power

Calderón Díaz, Alejandro (Date of defense: 2019-10-24)

Renewable energies have a major role in today’s energy systems development, energy security and climate change fight. Thermal Concentrating Solar Power (CSP) has the potential to get up to 11.3% of world’s electricity ...