Now showing items 38179-38198 of 42416

    Study of Structural and Sensing Properties of Tungsten Trioxide Thin Films Deposited By RF Sputtering 

    Vallejos Vargas, Stella (Date of defense: 2008-02-29)

    Hoy en día la habilidad de producir capas de óxidos metálicos compuestos por nanogranos es muy importante, no sólo como conocimiento fundamental, sino también desde un punto de vista industrial debido a las numerosas ...

    Study of structural changes in Zr-based bulk metallic glasses upon annealing and deformation treatments 

    Steenberge, Nele van (Date of defense: 2008-06-20)

    Los materiales conocidos como vidrios metálicos han sido sujeto de estudio e todo el mundo desde los años 50, por el cual se ha conseguido un progreso importante en el entendimiento del comportamiento de estos materiales. ...

    Study of surface chemistry strategies to enhance the electrochemical detection of proteins and DNA markers 

    Acero Sánchez, Josep Lluís (Date of defense: 2017-02-03)

    Els biosensors son dispositius analítics basats en la interacció específica entre un element biològic sensor i la seva molècula diana juntament amb un transductor per al processament de la senyal. Aquests dispositius tenen ...

    Study of Survival Motor Neuron protein regulation and the role of autophagy in Spinal Muscular Atrophy 

    Periyakaruppiah, Ambika (Date of defense: 2015-06-12)

    Spinal muscular atrophy (SMA) is a genetic disorder caused by loss of the Survival motor neuron 1 gene (SMN1), lead to reduced SMN protein level and selective dysfunction of MNs. SMN reduction causes neurite degeneration ...

    Study of synaptic proteins and neuronal cell death mechanisms in animal degenerative disorders 

    Sisó Llonch, Sílvia (Date of defense: 2002-07-29)

    La neuropatologia degenerativa inclou un grup de malalties que cursen amb la degeneració progresiva del teixit nerviós tant en animals com en persones, i causant una pèrdua neuronal i una reacció glial, majoritàriament ...

    Study of the ability of carboranylcarboxylate ligands to generate polynuclear compounds. Potential applications 

    Fontanet Cepeda, Mònica (Date of defense: 2013-11-22)

    In this thesis is presented the synthesis and characterization of two different carboranylcarboxylate ligands, 1-CH3-2-CO2H-1,2-closo-C2B10H10 and 1-CO2H-1,2-closo-C2B10H11, in which the methyl group bonded to the carbon ...

    Study of the aggregation process of the amyloid beta-protein associated to Alzheimer's disease. Examination of pharmaceutically important small molecules. 

    Serra Vidal, Bernat (Date of defense: 2014-05-27)

    Alzheimer’s disease (AD) is a neurodegenerative disorder which major risk factor is age. Current drugs only offer symptomatic alleviation in AD, thus a disease-modifying treatment is urgent. The amyloid-β (Aβ) protein ...

    Study of the algebraic structure of left braces and the yang-baxter equation 

    Bachiller Pérez, David (Date of defense: 2016-05-27)

    Aquesta tesi doctoral tracta de l’estructura algebraica anomenada braça no commutativa per l’esquerra, i de les seves aplicacions a les solucions conjuntistes no degenerades de l’equació de Yang-Baxter. Concretament, ...

    Study of the alterations in the intestinal and extra-intestinal microbiome in rats and humans throughout the progression of cirrhosis 

    Santiago Badenas, Alba (Date of defense: 2018-10-03)

    La microbiota intestinal desempeña un papel fundamental en el desarrollo del sistema inmune y en el mantenimiento de la homeostasis del huésped suprimiendo las respuestas a los patógenos y reforzando la integridad de las ...

    Study of the ammonia absorption process into ammonia/water solutions using polymeric membranes for absorption-resorption refrigeration systems 

    Berdasco Ruiz, Miguel Ángel (Date of defense: 2018-06-12)

    En aquesta tesi s’estudia el procés d’absorció d’amoníac en dissolucions d’amoníac/aigua utilitzant membranes polimèriques com a contactors per a la seva integració en els sistemes de refrigeració per absorció-resorció. ...

    Study of the anticancer activity of a nuclear directed HP-RNase variant and different metal-based compounds 

    Bravo Bonilla, Marlon Rolando (Date of defense: 2022-06-16)

    Cancer is the leading cause of death due to non-communicable diseases worldwide. Despite the advances in the development of new antitumor drugs, there are still problems such as the resistance that tumor cells acquire ...

    A study of the association between one carbon metabolism and blood pressure in adults and transgenerationally between pregnant women and their children. 

    Ornosa Martín, Gemma (Date of defense: 2019-10-25)

    El metabolisme monocarbonat i el polimorfisme MTHFR 677 C>T s’ha associat amb la pressió arterial i la hipertensió. Es creu que el mecanisme associat és la programació fetal. Un estat adequat de nutrients del metabolisme ...

    Study of the beam induced vacuum effects in the cryogenic beam vacuum chamber of the Future Circular Hadron Collider 

    Bellafont Peralta, Ignasi (Date of defense: 2021-01-25)

    The Future Circular Hadron Collider (FCC-hh) is a proposal for a 100 km long hadron collider conceived as the successor of the Large Hadron Collider (LHC). The FCC-hh is designed to reach 50 TeV of beam energy, greatly ...

    Study of the biological functions of the nonessential regulatory subunits of the protein phosphatase Glc7 in the yeast Saccharomyces cerevisiae 

    Ferrer-Dalmau Falgueras, Jofre (Date of defense: 2014-01-31)

    L’única subunitat catalítica de PP1 en S. cereivisiae, Glc7, interacciona amb un mínim de 31 subunitats reguladores que li permeten regular tot el ventall de funcions. En aquesta tesis, hem estudiat les soques delecionades ...

    Study of the characterization of the mechanical properties of materials with elastomeric behavior for biomedical applications 

    Adrover Monserrat, Bàrbara (Date of defense: 2023-02-24)

    (English) The mechanical characterization of new materials used in the Material Extrusion technique (MEX) in 3D printing is essential. The use of this technique is growing and with it the possible applications of printed ...

    Study of the components and adherence to the Mediterranean diet on functional and cognitive ageing: from dietary assessment to a metabolomic approach 

    Tor Roca, Alba (Date of defense: 2023-12-20)

    [eng] Healthy dietary patterns, such as the Mediterranean diet, have been linked to reduced chronic disease risk and mortality. However, the evidence regarding the impact of healthy dietary patterns on physical and cognitive ...

    Study of the components that determine the applicability of pathogenicity predictors in the clinical setting 

    Aguirre Gómez, Josu (Date of defense: 2020-07-14)

    The translation of Next Generation Sequencing (NGS) technologies from the research field to the clinical setting and, specifically, the results obtained in terms of diagnostic yield remain far from expected. This situation ...

    Study of the conformational dynamics of prolyl oligopeptidase 

    López Asamar, Abraham (Date of defense: 2015-07-17)

    Prolyl oligopeptidase (POP) is an 81-KDa bidomain enzyme which hydrolyses short proline-containing peptides. This enzyme is involved in mnemonic and cognitive processes, and the dysregulation of POP activity is related to ...

    Study of the contribution of ORMDL3 to the cannabinoid antitumoral action 

    García López, Roberto (Date of defense: 2018-04-06)

    Genome-wide association studies have been very useful tools in the last years to relate genes and diseases. Thereby, single nucleotide polymorphisms have been linked to increased ORMDL3 expression and to different pathologies ...

    Study of the cooperative effect of UVR, BRAF and LKB1 in melanoma 

    González Sánchez, Elena (Date of defense: 2019-06-14)

    Entender los mecanismos moleculares relacionados con la melanomagénesis es clave a la hora de encontrar nuevas estrategias preventivas y terapéuticas contra esta letal enfermedad. La epidemiología indica que hay factores ...