Browsing by Title

Functional profiling of the human gut microbiome using metatranscriptomic approach

Martínez Serrano, Xavier (Date of defense: 2020-02-26)

Fins ara, les aproximacions meta-òmiques utilitzen tecnologies de seqüenciació d'alt rendiment, que produeixen una quantitat enorme de dades, desafiant així els ordinadors moderns actuals. Hem desenvolupat una nova pipeline ...

Functional properties and applications of plasma polymerized hexamethyldisiloxane (ppHMDSO) thin films

Benítez i Porras, Francesc (Date of defense: 2016-01-29)

Plasma Polymerization is a novel technique for the preparation of polymer-like thin film coatings at low temperatures onto almost any type of substrates: plastic, metal, semiconductors, wood, textile fibers or membranes, ...

Functional responses of pre- and postsynaptic dopamine D2 receptors in rat brain striatum

Ma, Guofen (Date of defense: 2014-10-03)

El sistema dopaminèrgic has estat molt estudiat en els darrers anys, principalment degut a la seva implicació en diverses patologies com la malaltia de Parkinson, la esquizofrènia o la síndrome de Tourette, així com també ...

The functional role of emergent macrophytes in nature-based solutions (NBS) aiming to mitigate nutrient loading in freshwater ecosystems

Nikolakopoulou, Myrto-Georgia (Date of defense: 2021-01-29)

Freshwater degradation has been largely attributed to excess nutrient concentrations of anthropogenic origin. Freshwater degradation in combination with water scarcity are the reason of severe stress on water resources ...

Functional role of extracellular matrix proteins and their receptors in apoptosis and cell survival

Cardó i Vila, Marina (Date of defense: 2003-07-25)

Macrophages require presence of M-CSF to survive and proliferate. Incubation of bone marrow macrophages with soluble factors (LPS or IFN-gamma) or insoluble factors such as extracellular matrix proteins (Decorin, FN) ...

Functional Role of Glycogen synthase Kinase-3β on Glucocorticoid-mediated signaling

Rubio Patiño, Camila (Date of defense: 2012-10-31)

Glucocorticoids (GC) induce cell cycle arrest and apoptosis in different cell types and therefore are widely used to treat a variety of diseases including autoimmune disorders and cancer. This effect is mediated by the GC ...

Functional role of pentose phosphate pathway and glutamine in cancer cell metabolism

Polat, Ibrahim H. (Date of defense: 2016-11-04)

In this thesis, tumor metabolic reprogramming has been exploited in order to propose new targets in cancer treatment. On one hand, we explored the pentose phosphate pathway (PPP) enzymes as putative therapeutic targets ...

Functional studies of 4F2hc-CD147 interaction = Estudios funcionales de la interacción 4F2hc‐CD147

Delgado Martin, Gonzalo (Date of defense: 2014-07-14)

We identified proteins that interacted with the ectodomain of 4F2hc, a plasma membrane protein with dual function as heavy subunit of the amino acid transporters and positive regulator of β1 and β3 integrins. Initially, ...

Functional studies on the circadian regulation of mitochondrial activity in Arabidopsis thaliana

Cervela Cardona, Luis Manuel (Date of defense: 2019-11-21)

El reloj circadiano es un mecanismo celular endógeno capaz de medir el paso del tiempo y traducir las señales medioambientales, principalmente luz y temperatura, en respuestas temporales que resultan en ritmos metabólicos ...

Functional study of the NIMA protein kinases Nek9, Nek6 and Nek7 at the onset of mitosis. Control of the kinesin Eg5 and prophase centrosome separation

Eibes González, Susana (Date of defense: 2016-09-13)

Mitosis is a tightly regulated process that aims to ensure the correct distribution of the chromosomes between the two newly generated cells. Many protein kinases have been defined as essential for this process: cyclin- ...

Functional surfaces by means of nanoimprint lithography techniques

Fernández Estévez, Ariadna (Date of defense: 2016-11-25)

Diferentes funcionalidades pueden ser obtenidas en diversas superficies a través de topografía en lugar de química, inspirándose en la naturaleza. El principal objetivo de esta tesis es la investigación de la litografía ...

Functional surfaces obtained by thermal spray techniques

Robotti, Marco (Date of defense: 2016-09-29)

The main subject of this PhD Thesis is the manufacturing of titanium dioxide multifunctional coatings by means of two spraying technologies: Cold Gas Spray (CGS) and Atmospheric Plasma Spray (APS). The characteristics of ...

Functional, genomic and molecular characterisation of Mtl1, an element of the CWI pathway of Saccharomyces cerevisiae with a role in the oxidative stress response

Ivanova Petkova, Mima (Date of defense: 2011-09-16)

Saccharomyces cerevisiae és un microorganisme eucariota que s’utilitza com a model per l’estudi de les vies de transducció de senyal implicades en la resposta a estrès oxidatiu. Fins l’actualitat, no s’ha descrit ...