Now showing items 27586-27605 of 41875
González del Solar Sarría, Rafael (Date of defense: 2016-01-25)
La ecología es una ciencia importante, tanto desde el punto de vista práctico como desde el teórico, que recientemente a comenzado a atraer la atención de los filósofos profesionales. Con todo, la investigación sobre los ...
Venturini, Valeria (Date of defense: 2022-04-08)
Living tissues are crowded and dynamic environments, in which signalling molecules and physical forces constantly act on single cells. To ensure correct tissue development and homeostasis, cells function like small processors: ...
Barbero Castillo, Almudena (Date of defense: 2020-07-17)
Throughout various brain states, billions of neurons interact resulting in a variety of cortical rhythms accompanied by switches between behavioral states (Gervasoni et al., 2004). As a result of the specific (1) ...
Mateu Jiménez, Mercè (Date of defense: 2017-12-18)
Chronic respiratory diseases, especially chronic obstructive pulmonary disease (COPD), and several molecular mechanisms may predispose to lung cancer (LC) development. Hypothesis: We hypothesized that different biological ...
Bernadó Morales, Cristina (Date of defense: 2015-04-23)
In response to oncogenic stresses cells activate two different tumor suppressor mechanisms: Oncogene-induced senescence (OIS), a terminal cell proliferation arrest, or oncogene-induced apoptosis (OIA), which leads to cell ...
Banakar, Raviraj (Date of defense: 2016-02-05)
L’arròs es un cultiu bàsic, consumit per mes de 3 billons de persones. Es una font pobra en ferro (Fe) i zinc (Zn) per la qual cosa les poblacions pobres que depenen de l’arros per a la seva supervivència, sofreixen d’anèmia ...
Souza, Vitor Barbosa Carlos de (Date of defense: 2018-01-10)
Albeit several IoT applications have been recently deployed in several fields, including environment and industry monitoring, Smart Home, Smart Hospital and Smart Agriculture, current deployments are mostly host-oriented, ...
Tanovic, Adnan (Date of defense: 2003-06-13)
El objetivo de este estudio es evaluar los mecanismos neurales y musculares implicados en la contracción y la relajación del músculo longitudinal del intestino delgado de rata en condiciones control y tras la infestación ...
Diaz Lucena, Daniela Del Valle (Date of defense: 2016-12-15)
Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system characterized by a coordinated inflammatory attack on the myelin sheaths with ensuing damage to the underlying axons. Using ...
Guix Arnau, Marta (Date of defense: 2017-12-19)
Targeted therapies against the Epidermal Growth Factor Receptor (EGFR) are useful to treat many human cancers such as non-small cell lung cancer, colorectal cancer and head and neck cancer. However, the efficacy of such ...
Estruch Alrich, Montserrat (Date of defense: 2014-09-19)
L’LDL electronegativa (LDL(-)) és una LDL modificada present en circulació amb propietats inflamatòries incloent la inducció de l’alliberament de citoquines en cèl·lules relacionades amb l’arteriosclerosi, tals com monòcits ...
Lorente-Sorolla Martínez-Acítores, Clara (Date of defense: 2019-12-20)
This doctoral thesis describes the participation of epigenetic mechanisms, and more specifically DNA methylation, in innate immune responses against pathogens. Innate immunity is the first barrier of defense against ...
Toll i Riera, Macarena (Date of defense: 2012-03-28)
Actualment, degut a la disponibilitat d’un gran nombre de genomes seqüenciats, el camp de la genòmica comparativa està experimentant grans avenços. Ara són possibles una àmplia gama d’estudis que fins fa poc eren inimaginables. ...
Fàbrega Santamaria, Anna (Date of defense: 2010-11-24)
INTRODUCTION Quinolones are potent and broad spectrum antibacterial agents and, among them, several fluoroquinolones, such as ciprofloxacin, are the treatment of choice against several human infections. Resistance to ...
García de Albéniz, Xabier (Date of defense: 2015-04-15)
We studied the mechanisms driving the metastatic spread in colorectal cancer (CRC), focusing in the MAPK pathway. We developed in vivo a highly metastatic cell line using a KRAS-mutated cell line (SW620) in an ortothopic ...
Letelier Torres, Nicole Alejandra (Date of defense: 2021-12-14)
Obesity is nowadays considered a pandemic disease, and its incidence correlates with the concomitant increase of a set of associated comorbidities, including T2D, cardiovascular diseases, fatty liver disease, among others, ...
Salazar Degracia, Anna (Date of defense: 2019-04-15)
La caquexia afecta negativamente a los pacientes con enfermedades crónicas y sobre todo en el cáncer. Las estrategias terapéuticas son aún limitadas. Los beta2-agonistas (formoterol) y el soporte nutricional (L-carnitina) ...
Somerville, Rosemarie Janet (Date of defense: 2020-02-13)
Comprendre els mecanismes de les transformacions catalítiques és extremadament important, ja que permet als químics millorar les reaccions reduint, per exemple, la càrrega de catalitzadors, impedir la formació de subproductes ...
López Pelegrín, Maria del Mar (Date of defense: 2015-11-13)
Metallopeptidases are major players in the physiology and pathology of all living organisms. Their exquisite regulation is therefore essential for proper function and to prevent misdirected temporal and/or spatial proteolytic ...
Zhang, Junjie (Date of defense: 2018-06-20)
El cáncer de mama HER2-positivo representa alrededor del 15-30% del total de pacientes con cáncer de mama. Este subtipo tiene un mal pronóstico, seguido del subtipo Triple-negativo (TNBC), que lo tiene aún peor. Actualmente, ...