Now showing items 5209-5228 of 11039

    Función Muscular Periférica y Entrenamiento Físico en la Enfermedad Pulmonar Obstructiva Crónica. Relaciones entre estado Redox, inflamación y respiración mitocondrial. 

    Rabinovich Spinelli, Roberto Alejandro (Date of defense: 2005-09-28)

    La intolerancia al ejercicio que sufren los pacientes con EPOC se debe no solo a factores pulmonares sino a la disfunción de músculos periféricos presente en este grupo de pacientes que se engloba dentro de los denominados ...

    Function and brain structure in aging with and without cognitive impairment 

    Solé Padullés, Cristina (Date of defense: 2007-11-09)

    L'interès general d'aquest projecte de tesi doctoral es centra en l'estudi dels patrons d'activació cerebral subjacents a l'envelliment cognitiu, tant en condicions clíniques normals com patològiques (Alteració cognitiva ...

    Function and Operator Theory on Large Bergman spaces 

    Arroussi, Hicham (Date of defense: 2016-05-06)

    The theory of Bergman spaces has been a central subject of study in complex analysis during the past decades. The book [7] by S. Bergman contains the first systematic treat-ment of the Hilbert space of square integrable ...

    Function and Regulation of Bone Morphogenetic Protein 7 (BMP7) in Cerebral Cortex Development 

    Ortega Cano, Juan Alberto (Date of defense: 2011-09-30)

    Brain derived neurotrophic factor (BDNF) is a chemokine which levels are regulated by neuronal activity and could act as a sensor in front of distinct physiologic stimulus, activating the transcription of specific group ...

    Function of the histone demethylase PHF8 in neural progenitor cells and glial differentiation 

    Iacobucci, Simona (Date of defense: 2021-03-18)

    Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural stem cells biology. To ...

    Functional analyses of candidate genes for osteoporosis : RUNX2 and LRP5 interplay during differentiation of the hFOB human osteoblast cell line 

    Gholami, Behjat (Date of defense: 2017-09-18)

    Osteoporosis is a general skeletal disorder. It is characterized by a low bone mass and a microarchitectural deterioration of bone tissue, which increase bone fragility and susceptibility to fracture. LRP5 is a widely ...

    Functional analysis of a phloem cysteine protease in Arabidopsis thaliana 

    Pitsili, Eugenia (Date of defense: 2021-11-04)

    Metacaspases are a family of cysteine proteases found in lower eukaryotes and plants. They are considered to be distant relatives of caspases, present only in animals. The role of metacaspases is quite diverse, from ...

    Functional analysis of EXD2 in mitochondrial homeostasis 

    Faria da Silva, Joana Raquel (Date of defense: 2017-03-24)

    One of the most fundamental events in the history of life is the origin of mitochondria. It was firstly proposed by Ivan Wallin, and later popularized by Lynn Margulis, as part of the endosymbiotic theory, that mitochondria ...

    Functional analysis of variant proteins in Plasmodium vivax: Implications in pathology 

    Bernabeu Aznar, Maria (Date of defense: 2013-06-14)

    P. vivax is the most widespread malaria, it accounts for 25-40% of the global disease burden and it is estimated that causes from 132 to 391 million clinical cases each year. It is amply accepted that P. vivax do not ...

    Functional and molecular characterization of maize open stomata 1 protein kinase 

    Vilela, Belmiro (Date of defense: 2012-12-18)

    Plant growth and productivity are compromised by environmental stresses such as pathogens, extreme temperatures, drought and high salinity. Being sessile organisms, plants had to develop different physiologic and biochemical ...

    Functional and Phylogenetic Diversity of Amphibians in the Brazilian Atlantic Forest: Implications for a Systematic Conservation Planning 

    Siqueira Campos, Felipe (Date of defense: 2018-06-18)

    Biodiversity patterns are results of ecological and evolutionary processes. Understanding the forces shaping biodiversity patterns help to predict the responses of ecosystems to environmental change. Considering the role ...

    Functional characterization of AWR affector proteins from the phytopathogen "R. solanacearum" (Caracterització funcional de les proteïnes efectores AWR del fitopatogen "R. solanacearum") 

    Solé Castellví, Montserrat (Date of defense: 2011-11-25)

    "R. solanacearum" is a devastating bacterial pathogen that infects "Solanaceae" spp. such as tomato, eggplant or banana. A functional T3SS is required for virulence and more than 70 putative effectors have been described, ...

    Functional characterization of single amino acid variants 

    López Ferrando, Víctor (Date of defense: 2019-12-11)

    Single amino acid variants (SAVs) are one of the main causes of Mendelian disorders, and play an important role in the development of many complex diseases. At the same time, they are the most common kind of variation ...

    Functional design of nanocomposites and their applications in energy conversion and storage 

    Du, Ruifeng (Date of defense: 2022-06-30)

    [eng] This thesis focuses on the functional design and preparation of different kind of nanocomposites and their applications in energy conversion and storage technologies, particular in OER, HER, H2O2ER and LSBs. For the ...

    Functional genomics of wound healing in drosophila = Genòmica funcional del procés de cicatrització en drosophila 

    Tamirlsa, Srlvldya (Date of defense: 2014-07-14)

    La ciencia básica ha de engarzarse con las necesidades sociales. Así, nuestro laboratorio esta involucrado en identificar genes específicamente modulados durante el proceso de cicatrización mediante estudios transcriptómicos ...

    Functional interplay between ER and MAF transcription factors in breast cancer bone metastasis 

    Llorente Lope, Alicia (Date of defense: 2021-03-23)

    Metastatic breast cancer (BCa) is the leading cause of death in BCa patients. Current therapies for BCa aim at cell proliferation and, therefore, latent disseminated cells are able to escape treatment. For this reason, ...

    Functional interplays of proteins and proteases: AD13-VWF, TGFβ2-α2M, and the proteolysis of gliadin by neprosin 

    Amo Maestro, Laura del (Date of defense: 2021-06-11)

    The present thesis has established a new and state of the art mammalian protein expression system at the laboratory which has then contributed with high-yield expression for the purification and crystallization of three ...

    Functional Nanomaterials from the Bottom-up Assembly of Colloidal Nanoparticles. A Strategy Towards Efficient Thermoelectrics 

    Ibáñez Sabaté, Maria (Date of defense: 2013-03-05)

    The work developed during this PhD has embraced several topics that I divide in three blocks. Each block contains two chapters in this dissertation. Additionally, a general introduction of the different topics is provided ...

    Functional organization and networ resilience in self-organizing clustered neuronal cultures 

    Teller Amado, Sara (Date of defense: 2016-02-05)

    Major dynamical traits of a neuronal network are shaped by its underlying circuitry. In several neurological disorders, the deterioration of brain's functionality and cognition has been ascribed to changes in the topological ...