Mostrando ítems 1-10 de 15
Tarrado Castellarnau, Miriam Neus (Fecha de defensa: 2015-12-11)
Cancer is characterised by the lost of physiological control and the malignant transformation of cells that acquire functional and genetic abnormalities, leading to tumour development and progression. ...
Aguilar Fadó, Esther (Fecha de defensa: 2015-02-23)
Metastasis represents the most life-threatening aspect of tumorigenesis and is the leading cause of death by cancer. Intensive research in this field has shed light on some of the molecular strategies ...
Matito Sánchez, Cecilia (Fecha de defensa: 2006-01-13)
Cancer is one of the leading causes of death in countries throughout the world. Increase in the production of Reactive Oxygen Species (ROS) has been implicated in many human disease processes, including ...
Sánchez Tena, Susana (Fecha de defensa: 2012-07-27)
La present Tesi Doctoral es centra en l'estudi de l'efecte de diferents compostos d'origen natural sobre el càncer de còlon. La Tesi s'estructura en dues parts: la primera in vitro basada en estudis amb ...
Carreras Cardona, Anna (Fecha de defensa: 2012-05-04)
During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical ...
Tarragó Celada, Josep (Fecha de defensa: 2020-09-16)
Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better ...
Balcells Nadal, Cristina (Fecha de defensa: 2019-12-19)
Metastasis and drug resistance represent the two main causes of therapeutic failure in oncology. In the present dissertation, the interplay between them has been interrogated using metabolomics, systems ...
Cortés Giràldez, Roldàn (Fecha de defensa: 2014-07-30)
El propósito de esta Tesis Doctoral es el de explorar nuevas posibilidades de tratamiento y de diagnóstico del cáncer de pulmón, y concretamente del cáncer de pulmón no microcítico de células con ...
Polat, Ibrahim H. (Fecha de defensa: 2016-11-04)
In this thesis, tumor metabolic reprogramming has been exploited in order to propose new targets in cancer treatment. On one hand, we explored the pentose phosphate pathway (PPP) enzymes as putative ...
Zodda, Erika (Fecha de defensa: 2019-12-13)
The endothelium plays a pivotal role in the development of cardiovascular disease (CVD) and emerging evidence indicates that pathological blood vessel responses and endothelial dysfunction are associated ...