Tarrado Castellarnau, Miriam Neus (Date of defense: 2015-12-11)
Cancer is characterised by the lost of physiological control and the malignant transformation of cells that acquire functional and genetic abnormalities, leading to tumour development and progression. ...
Aguilar Fadó, Esther (Date of defense: 2015-02-23)
Metastasis represents the most life-threatening aspect of tumorigenesis and is the leading cause of death by cancer. Intensive research in this field has shed light on some of the molecular strategies ...
Matito Sánchez, Cecilia (Date of defense: 2006-01-13)
Cancer is one of the leading causes of death in countries throughout the world. Increase in the production of Reactive Oxygen Species (ROS) has been implicated in many human disease processes, including ...
Sánchez Tena, Susana (Date of defense: 2012-07-27)
La present Tesi Doctoral es centra en l'estudi de l'efecte de diferents compostos d'origen natural sobre el càncer de còlon. La Tesi s'estructura en dues parts: la primera in vitro basada en estudis amb ...
Carreras Cardona, Anna (Date of defense: 2012-05-04)
During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical ...
Tarragó Celada, Josep (Date of defense: 2020-09-16)
Metastasis is the main cause of cancer-related deaths and it is of great biomedical importance to develop new therapeutic strategies that specifically target metastatic cells. Therefore, a better ...
Cortés Giràldez, Roldàn (Date of defense: 2014-07-30)
El propósito de esta Tesis Doctoral es el de explorar nuevas posibilidades de tratamiento y de diagnóstico del cáncer de pulmón, y concretamente del cáncer de pulmón no microcítico de células con ...
Polat, Ibrahim H. (Date of defense: 2016-11-04)
In this thesis, tumor metabolic reprogramming has been exploited in order to propose new targets in cancer treatment. On one hand, we explored the pentose phosphate pathway (PPP) enzymes as putative ...
Zodda, Erika (Date of defense: 2019-12-13)
The endothelium plays a pivotal role in the development of cardiovascular disease (CVD) and emerging evidence indicates that pathological blood vessel responses and endothelial dysfunction are associated ...
Baptista, Inês do Carmo Viegas (Date of defense: 2022-04-07)
Leukaemia is one of the types of cancer where treatment resistance is prevalent. Better understanding of leukemic cells metabolism opens possibilities for new therapeutic strategies and better prognosis ...