Rojas Expósito, Luis Alfonso (Date of defense: 2017-05-26)
Cancer virotherapy with oncolytic adenoviruses represents a promising therapeutic approach due to the capacity of these viruses to infect and selectively kill tumor cells without damaging normal tissues. ...
Hospital Gasch, Adam (Date of defense: 2014-10-13)
Macromolecular structure, and, specifically, its dynamics and flexibility, play a crucial role in its final biological function. Intense efforts are being made to obtain experimental information about ...
Rodríguez Gallego, Laura (Date of defense: 2015-03-13)
The work presented in this thesis is focused on the study of Polypurine Reverse Hoogsteen hairpins (PPRHs) as gene silencing tools. PPRHs are double-stranded DNA molecules formed by tvvo anti parallel ...
dos Reis Mendes, Soraia Inês (Date of defense: 2022-10-28)
[eng] Several proteases and their antagonistic protein or peptide inhibitors sparked researchers’ interest due to their potential as therapeutic targets. The present thesis, which compiles results ...