Rodón Ahnert, Laura (Date of defense: 2012-11-28)
The TGF-β pathway is currently considered a therapeutic target in advanced tumors, including glioblastoma (GBM), and several anti-TGFβ agents are in clinical trials and have shown promising results .A ...
Celià Terrassa, Antoni (Date of defense: 2012-05-14)
This Doctoral Thesis project is part of a broader research program whose global aim is to better understand key molecular and cellular events in tumor metastasis, in particular those associated with ...
Villalobos Alberú, Xenia (Date of defense: 2015-12-22)
This work is focused on the study of the stability and immunogenic properties of the Polypurine Reverse Hoogsteen hairpins (PPRHs), and on their use as a gene-silencing tool. PPRHs are non-modified DNA ...