Carreras Gallo, Natàlia (Date of defense: 2023-03-24)
DNA methylation is really important because it is altered due to genetic and environmental factors, and it is associated with common diseases. In this thesis, we identified new factors altering DNA ...
Torregrosa Cortés, Gabriel (Date of defense: 2023-09-29)
This thesis is about development and its study from a theoretical point of view, with special interest in how to describe development as a dynamical systems' problem. The thesis digs into four directions ...
Serradell Noguera, Jose Miguel (Date of defense: 2024-03-01)
Since the first peopling of the region, multiple demographic events have occurred generating a complex genetic landscape in North Africa characterized by high genetic heterogeneity and constant gene ...
Martin, Olivier M. F. (Date of defense: 2022-04-05)
Gràcies als amplis esforços d'investigació, la nostra comprensió dels mecanismes fisiològics de l'envelliment ha progressat enormement. Recentment, les tecnologies òmiques han permès l'estudi a tot el ...
Mogas Diez, Sira (Date of defense: 2022-01-28)
This PhD thesis explores the potential embedded in living organisms, understood as highly complex machines which can sense, compute, and react to changes in their surroundings. From this general idea, ...
Delgado Tejedor, Anna (Date of defense: 2024-03-21)
RNA modifications, collectively known as the ‘epitranscriptome’, play a major role in multiple biological processes, including splicing regulation, gene expression regulation and antibiotic resistance. ...
San José Plana, Adrià (Date of defense: 2024-04-16)
The primary goal of this PhD is to deepen our understanding and improve the modeling capacity of zoonotic spillover, the multilevel process by which pathogens manage to overcome a series of natural ...
Elek, Anamaria (Date of defense: 2024-04-19)
Single-cell genomics methods have revolutionized the study of gene expression and regulation at the cell type level. Generating single-cell atlases for species at key phylogenetic positions of the animal ...
Martín de Dios, Laura (Date of defense: 2024-05-06)
La organización del genoma en células mamíferas sigue siendo en gran parte desconocida. Un nivel fundamental de organización se considera el bucle de cromatina, que consiste en una región de ADN atrapada ...
Besedina, Elizaveta (Date of defense: 2023-05-12)
Determinar qué genes están bajo selección durante la evolución del cáncer puede explicar cómo se forman y progresan los tumores, y sugerir nuevos objetivos terapéuticos. Sin embargo, la detección de ...