Baltzis, Athanasios (Date of defense: 2023-03-20)
Recent advances in deep learning techniques have revolutionised protein structure modelling. Since AlphaFold2’s release, a set of tools have now become available to predict native-like structures at ...
Tolosa Ramon, Queralt (Date of defense: 2023-07-26)
The outer epithelial layer is the first cell type that emerges during development, providing essential mechanical protection and is indispensable for morphogenesis. Here, we study how the interplay ...
Engel-Pizcueta, Carolyn (Date of defense: 2023-04-28)
The generation of cell diversity in the embryonic brain relies on the balance between cell proliferation and differentiation. The hindbrain boundary cells specify at the interface between adjacent ...
Gignac, Florence (Date of defense: 2022-07-07)
The short-term effects of air pollution on brain health have come under investigation only recently. Since environmental health studies are often developed entirely by scientists, citizen science is a ...
Pardo Lorente, Natalia (Date of defense: 2023-10-06)
Subcellular compartmentalisation of metabolic enzymes may elicit specific cellular functions by establishing a unique metabolic environment. Indeed, the nuclear translocation of certain metabolic enzymes ...
Soria Jiménez, Luis (Date of defense: 2023-02-17)
Although the dual anti-HER2 blockade with trastuzumab and pertuzumab monoclonal antibodies has improved the outcome of patients with HER2+ breast cancer, a significant number of patients relapse. ...
Ruiz-Giralt, Abel (Date of defense: 2023-12-13)
The present study expands our understanding of human-environment interactions in drylands throughout time, with a specific focus on the development of resilient agroecological systems based on Traditional ...
Porcaro, Lorenzo (Date of defense: 2022-12-16)
This thesis focuses on assessing the impact that music recommendation diversity may have on listeners. In the music domain, diversity is one of the values that recommender systems should preserve, ...
Alvarez Estapé, Marina (Date of defense: 2023-04-20)
The field of genomics can be used to help in threatened species conservation by guiding conservation efforts. In this thesis we have studied Cuvier’s gazelles to compare the genetic diversity and ...
Barrero Asencio, Mercedes (Date of defense: 2023-03-02)
During reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), the epigenome needs to be reset. A prime example of this is the reversal of the silent state of the inactive X chromosome ...