Caballero de la Torre, María (Date of defense: 2021-09-09)
Retinoblastoma protein (RB) is a negative regulator of the cell cycle. In response to environmental stress, p38 MAPK phosphorylates RB in the N-terminal region, increasing the affinity of RB for E2F, ...
Stojakovic, Predrag (Date of defense: 2023-03-06)
Cell volume regulation is essential for cellular homeostasis and adaptation to environmental osmotic changes. Upon hyperosmotic stress, cells need to rapidly restore osmotic balances in order to preserve ...
Latorre Doménech, Pablo (Date of defense: 2021-06-15)
Virtually all living organisms are challenged by changes in their environment, such as sudden increases in osmolarity. To cope with these stresses, cells have developed stress responses that tune every ...
Pijuan Calvet, Anna (Date of defense: 2021-09-14)
Yeast deal with continuous environmental perturbations that compromise its cell fitness. Upon osmostress, HOG pathway becomes activated and leads the adaptation response. To compensate the osmotic ...