Mariotti, Marco (Date of defense: 2013-12-13)
Selenoproteins are a diverse class of proteins containing selenocysteine, the 21st aminoacid. Selenocysteine is inserted co-translationally, recoding very specific UGA codons through a dedicated ...
Rodríguez Galindo, Miguel (Date of defense: 2023-11-13)
Tumor progression is dominated by two evolutionary forces: first mutagenesis, which provides the heritable variability where, secondly, natural selection acts. The main challenge of cancer genomics is ...
Piñero González, Janet (Date of defense: 2015-12-17)
In the last two decades, the volume and variety of biomedical data has dramatically increased. The data is heterogeneous and scattered across many resources. This produces bottlenecks in the analysis ...
Aterido Ballonga, Adrià (Date of defense: 2019-02-26)
Rheumatoid arthritis, psoriasis, psoriatic arthritis, systemic lupus erythematosus, Crohn’s disease and ulcerative colitis are six of the most prevalent immune-mediated inflammatory diseases (IMIDs) and ...
López Escardó, David (Date of defense: 2018-01-15)
Opisthokonta is an eukaryotic supergroup that contains Metazoa, Fungi and their unicellular relatives. Therefore, this group provides an ideal framework to study distinct unicellular-multicellular ...
Pohl, Andy (Date of defense: 2014-10-03)
Genome-wide analysis of the nucleosome positioning and histone H1 isoform content of the T47D breast cancer cell line has found a number of observations, namely that with a gentle digestion of microccocal ...
Han, Sojung (Date of defense: 2019-10-16)
Bonobos are an interesting species to study due to their unique evolutionary features such as a peaceful social nature and hypersexual behavior. The prolonged exaggerated sexual swelling in females ...
Domènech Salgado, Laura (Date of defense: 2018-12-20)
To date, very little progress has been made towards elucidating the genetic causes of obsessive-compulsive disorder (OCD). In this project we have performed rare variant association study (RVAS) ...
Prado Martínez, Javier (Date of defense: 2014-12-22)
Els grans simis són els nostres parents evolutius més propers i com a tals són la millor eina per entendre els nostres orígens més recents. Mitjançant la genòmica comparativa ara podem estudiar en ...
Rubio Pérez, Carlota (Date of defense: 2017-11-28)
Cancer is a disease of the genome. The study of tumor genomic alterations is used to guide several precision medicine strategies, some approved and a large number under clinical development. On the other ...