Mostrando ítems 90-109 de 229
Querejeta Coma, Marina (Fecha de defensa: 2017-07-21)
The study of intraspecific diversity is essential in ecology and evolution as they reveal fine-scale patterns and it is crucial in conservation planning. The main aim of this thesis is to study the evolutionary history of ...
Rotger Vallespir, Andreu (Fecha de defensa: 2016-11-30)
Many topics in ecology and evolution are currently being studied under the framework of eco- evolutionary dynamics that is to say integrating genetic, ecological and demographic data. Here, I have focused my investigations ...
González Nieto, Jèssica (Fecha de defensa: 2021-03-23)
La cromatina és una estructura nucleoproteïca dinàmica i jeràrquicament organitzada dins del nucli cel·lular. Segons la seva funcionalitat, la cromatina es pot classificar en dos tipus de regions: l’eucromatina, també ...
Alibakhshi, Esmaeil (Fecha de defensa: 2019-12-13)
INTRODUCTION: Patients with chronic respiratory disease (CRDs) have a disorder in muscle structure and function, but their function increases with physical progress and decreases the risk of general and muscular weakness. ...
Franco Valls, Héctor (Fecha de defensa: 2022-05-26)
SNAIL1 is a transcription factor with roles in repression of epithelial genes and enhancement of mesenchymal genes. As such, it plays a key role in Epithelial-to-mesenchymal transition and in fibroblast activation into ...
Carvalho Simoes, Francisco Manuel de (Fecha de defensa: 2018-07-06)
Glucose transporters (GLUTs) are extremely important for glucose metabolism. Glucose transporters uptake glucose from blood stream into the cells where it can be metabolized. Among the glucose transporters family, GLUT4, ...
Alonso Parrilla, Lorena (Fecha de defensa: 2023-01-16)
[eng] One of the major and most challenging goals of Biomedicine during the last centuries has been the study of the human biological mechanisms, and its relation with traits and diseases. Particularly, in the case of ...
Iacobucci, Simona (Fecha de defensa: 2021-03-18)
Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural stem cells biology. To ...
López Ferrando, Víctor (Fecha de defensa: 2019-12-11)
Single amino acid variants (SAVs) are one of the main causes of Mendelian disorders, and play an important role in the development of many complex diseases. At the same time, they are the most common kind of variation ...
Llorente Lope, Alicia (Fecha de defensa: 2021-03-23)
Metastatic breast cancer (BCa) is the leading cause of death in BCa patients. Current therapies for BCa aim at cell proliferation and, therefore, latent disseminated cells are able to escape treatment. For this reason, ...
Norris, Richard (Fecha de defensa: 2021-10-13)
Insulinomas are extremely rare pancreatic neuroendocrine (PNET) tumours that develop from the β-cells of the pancreas.β-cells are the only cells capable of producing the hormine insulin, and play a major role in glucose ...
Serra Vinardell, Jenny (Fecha de defensa: 2015-09-18)
La malaltia de Gaucher (GD) forma part d'un conjunt de malalties que es coneixen amb el nom de "malalties d'acumulació lisosómica". La GD n'és la més prevalent i en la majoria de casos és causada per mutacions en el gen ...
Matas Gironella, Júlia (Fecha de defensa: 2021-12-20)
Colorectal cancer (CRC) is a major health burden with large numbers of new cases worldwide and high disease-specific mortality, despite great advances made towards improving patient clinical outcomes. It arises through the ...
Rojas Salarich, Itziar de (Fecha de defensa: 2023-07-05)
[eng] Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Research in the past decade has led to major progress in understanding the genetic etiology of the disease; since I started my PhD (2019), nearly ...
Vilar Ribó, Laura (Fecha de defensa: 2023-11-20)
[eng] Substance use disorders (SUDs) are psychiatric disorders characterized by a recurring desire to continue taking a substance regardless of its destructive consequences. The etiology of SUDs is complex and multifactorial, ...
Turón Rodrigo, Gemma (Fecha de defensa: 2019-04-25)
Colorectal tumors are not homogeneous entities but rather composed of a mixture of cells with different phenotypes, reminiscent of healthy intestinal epithelium cell types. Intestinal epithelium is one of the organs with ...
Casso Carrasco, Maria (Fecha de defensa: 2020-03-12)
Invasive species constitute a major threat to global biodiversity and cause important economic losses and ecological impacts. In the marine realm, ascidians include several aggressive invasive species, some of which have ...
Garate Amenabarro, Leyre (Fecha de defensa: 2017-09-01)
El estudio se centra la filogenia, biología y ecología de la demosponja Hemimycale columella y su simbiosis con una bacteria calcificadora (calcibacteria). Posteriormente se incorporaron otras especies para entender tanto ...
Muñiz Pérez, Diana (Fecha de defensa: 2013-10-29)
Los hongos calicioides es un grupo artificial de hongos, liquenizados y no-liquenizados, que se incluían dentro del antiguo orden Caliciales, y que ahora se mantienen agrupados debido la similar morfología de sus apotecios ...
Janatian, Nasime (Fecha de defensa: 2021-08-27)
In the present thesis we focus on the two extremes of the wind speed – storms and atmospheric stilling – and analyse their impacts on lake environments and phytoplankton dynamics over short and long periods. As we realised ...