Ara mostrant els elements 11-20 de 48
Deniz, Ozgen (Data de defensa: 2014-05-06)
The nucleosome is the fundamental structural unit of DNA compaction in eukaryotic cells and is formed by the wrapping of 147 bp double stranded DNA around a histone octamer. Nucleosome organization plays ...
Turón Rodrigo, Gemma (Data de defensa: 2019-04-25)
Colorectal tumors are not homogeneous entities but rather composed of a mixture of cells with different phenotypes, reminiscent of healthy intestinal epithelium cell types. Intestinal epithelium is one ...
Aragón Altarriba, Eric (Data de defensa: 2013-12-13)
Cell fate is controlled by a multitude of signals and loss of this control has devastating consequences for living organisms. One of the key players in this network of signals is the TGF-beta family of ...
Maíllo Carbajo, Carlos (Data de defensa: 2016-06-21)
The Cytoplasmic Polyadenylation Element Binding (CPEB)-family of RNA-binding proteins is composed of four paralogs in mammals, CPEB1-4. The CPEBs control the translation of the targeted mRNAs by modulating ...
Ezquerra González, Artur (Data de defensa: 2019-06-27)
Microtubules (MTs) mediate a range of essential cellular processes including cell division, intracellular transport and organelle positioning, by forming specifically adapted arrays. Assembly, maintenance ...
Benítez Amaro, Aleyda (Data de defensa: 2022-12-22)
[eng] BACKGROUND: Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty acid metabolism and glucose homeostasis. In the context of dyslipidemia, LRP1 is positively regulated ...
Vitos Faleato, Jessica (Data de defensa: 2018-01-19)
Tumors evolve by sequentially acquiring genetic abnormalities, like K-Ras activation and Tp53 loss of function, which enable transformed cells to survive, proliferate, invade, and reprogram their ...
Fernández Carasa, Irene (Data de defensa: 2021-06-29)
Parkinson’s disease (PD) is an incurable, chronically progressive disorder of old age leading to premature invalidity and death. Clinically, PD is characterized by classical motor syndrome linked to a ...
Català Moll, Francisco (Data de defensa: 2020-06-08)
Epigenetic factors, such as histone post-translational modifications and DNA methylation, are critical determinants of gene expression, which ultimately defines cell identity and function. Despite intense ...
Barranco Muñoz, Neus (Data de defensa: 2020-06-22)
The regulated secretory pathway is a hallmark of professional secretory cells as neurons and endocrine cells. Significant peptidergic neurotransmitters as hormones, neurotrophins and growth factors ...