Santos Tapia, Celia (Date of defense: 2019-10-30)
Aneuploidy, defined as a chromosome number that deviates from a multiple of the haploid set, is a common feature in human cancer, and around 70% of human solid tumours are aneuploid. The resulting ...
Soy Platero, Judit (Date of defense: 2014-07-17)
Arabidopsis thaliana seedling growth and development is influenced by both external (such as light and temperature) and internal (like hormones or circadian clock) factors. In short-day (SD) growing ...
Louzao Boado, Ánxela (Date of defense: 2019-04-30)
Genetically tractable models such as Drosophila melanogaster may help to identify new approaches to halt malignant growth. During my doctoral thesis, I performed a screen to find mitochondrial genes ...
Lorenzo Vivas, Erica (Date of defense: 2013-11-05)
IPSC are potent tools in the creation of disease models for both basic studies on the disease and testing of potential therapeutical drugs. In this context, it has been developed the derivation of iPSC ...
Corujo Garcia, David (Date of defense: 2019-12-10)
In the eukaryotic cell nucleus, DNA is tightly wrapped around histone complexes, forming a dynamic structure known as chromatin. The nucleosome particle is the basic repeating unit of the chromatin fiber ...
Bonàs Guarch, Sílvia (Date of defense: 2017-01-13)
The major landmark in modern genomic and biological research has been the first survey of the entire human genome. On June 2000 the staging of Bill Clinton along with Craig Venter and Francis Collins ...
González Rosado, Santiago (Date of defense: 2016-04-28)
The genetic and molecular bases of most of the human diseases have become one of the main goals of the human biology in the last decades. To be able to unveil the genetic variations and the affected ...