Aseeri, Mazen (Date of defense: 2023-03-13)
[eng] The main goals of this PhD thesis are closely related within the field of CDases and their key role in the regulation of sphingolipid metabolism. Thus, the roles of ACER3 and AC in different human ...
Deniz, Ozgen (Date of defense: 2014-05-06)
The nucleosome is the fundamental structural unit of DNA compaction in eukaryotic cells and is formed by the wrapping of 147 bp double stranded DNA around a histone octamer. Nucleosome organization plays ...
Romero Durana, Miguel Alfonso (Date of defense: 2018-11-26)
Proteins play a crucial role in virtually every biological process taking place within our cells. Most of the times, proteins do not participate in these processes alone but forming complexes of two or ...
Tello Velasco, Daniel (Date of defense: 2023-09-19)
[eng] For this purpose, Spatial Analysis of Functional Enrichment (SAFE) framework was proposed to uncover functional regions in a network by embedding it in 2-dimensions (2D) using the Spring embedding ...
Amengual-Rigo, Pep (Date of defense: 2021-02-15)
Proteins are large macromolecules constituted by amino acids that are responsible for most of the biological processes within a cell. Proteins showing high complementary affinity may bind forming ...
Doria Belenguer, Sergio (Date of defense: 2023-10-07)
[eng] Advances in capturing technologies have yielded a massive production of large-scale molecular data that describe different aspects of cellular functioning. These data are often modeled as networks, ...
Trujillano Fernández, Alejandro (Date of defense: 2024-02-08)
[eng] DYRK1A is a kinase that is expressed in virtually all tissues and cell types and is implicated in human diseases. Several studies indicate that DYRK1A is a dose-dependent gene with a prevalent ...