Universitat de Barcelona
Now showing items 21-40 of 47
Mitosis is a process that ensure the correct distribution of the chromosomes between the two newly generated cells, is tightly regulated by two main processes, protein degradation controlled by the APC and protein ...
Targeting cancer metastasis has gained considerable importance in the recent years when aiming to increase patients’ overall survival. In Renal Cell Carcinoma (RCC), the discovery of metastatic biomarkers and targets is ...
Lysosomes are the primary degradative organelles in mammalian cells. Indeed, lysosome enzymatic cocktail allows the degradation of a vast repertoire of cellular material through different converging pathways including ...
Els nounats neixen amb un sistema immunitari immadur, que es desenvolupa durant les primeres etapes de la vida. Aquesta immaduresa és més acusada en nadons prematurs. La llet materna conté nombrosos factors bioactius, com ...
En els darrers anys, la influència de l’exercici físic intens i extenuant ha guanyat molt d’interès, per una banda, pels efectes perjudicials que pot causar tant al sistema immunitari innat com a l’adaptatiu, i per altra ...
El sistema inmunitario no es totalmente funcional en el momento del nacimiento, sino que va desarrollando su capacidad defensiva frente a patógenos durante las primeras etapas de vida. Esta inmadurez en la respuesta ...
Los triterpenos pentacíclicos y polifenoles son compuestos bioactivos con propiedades saludables que se encuentran en plantas medicinales y comestibles, incluyendo Olea europaea L. En la tesis presentada se ha llevado a ...
This thesis is centered on the study of PolyPurine Reverse Hoogsteen (PPRH) hairpins technology as a tool for both gene silencing and gene editing. PolyPurine Reverse Hoogsteen (PPRH) hairpins are nonmodified single-stranded ...
Mycoplasma pneumoniae y Mycoplasma genitalium son dos patógenos humanos que infectan tejido pulmonar y urogenital respectivamente. El mecanismo principal para llevar a cabo la infección es a través de la adhesión a las ...
Obesity is the most common metabolic disorder that have alarmingly increased all over the world in the last few decades. The hormone insulin is one of the major endocrine axis deregulated in obesity and will be the focus ...
Table olives are an important source of phenolic compounds, whose beneficial health effects have been widely demonstrated. Therefore, the present thesis aims to assess the different phenolic compounds in Arbequina table ...
The nuclear receptors (NR) modulate gene transcription in a ligand-dependent manner throughout different mechanisms. A set of NR, including PPARγ and LXR, are important regulators of carbohydrate and lipid metabolism as ...
This work is focused on the study of Polypurine Reverse Hoogsteen hairpins (PPRHs) as a gene silencing tool, and on the search of alternative methods for their delivery, including viral and non-viral vectors. PPRHs are ...
Las aceitunas son una fuente dietética importante de compuestos bioactivos, entre los que destacan los triterpenos pentacíclicos. A estos componentes se les ha atribuido importantes propiedades beneficiosas para ...
The gut microbiota establishes dynamic and complex interactions with the intestinal epithelium and the immune system. In this regard, commensal microbiota plays essential role in the development and maturation of the host ...
Corpora amylacea (CA) in the human brain are polyglucosan aggregates that were first described by J.E. Purkinje in 1837. They are intracellular astrocytic bodies that accumulate mainly in perivascular, periventricular and ...
El Se és un micronutrient essencial que participa en diferents funcions en humans i en animals a través de la seva incorporació en forma de selenocisteïna (Sec) a les selenoproteïnes. Una ingesta inadequada de Se es considera ...
El sistema immunitari del nounat és immadur i, per tant, predisposa al nadó a patir infeccions, que en el cas dels nounats del gènere masculí semblen presentar una incidència i una gravetat majors que el femení. La llet ...
La malaltia d’Alzheimer (AD) és el tipus de demència més comú durant l’envelliment i una de les malalties neurodegeneratives més severes. L’AD es caracteritza per una pèrdua de memòria, la deposició de pèptids beta- amiloides ...
[eng] The influence of exercise on immune system has gained increasing attention from researchers lately, mainly due to the growing participation of the general population in sport competitions. Whereas moderate intensity ...
