López Blanch, Laura (Date of defense: 2021-04-30)
Neural microexons are the most conserved type of alternative splicing, suggesting a strong functional relevance. Consistently, mutation of their master regulators leads to dramatic neurodevelopmental ...
Pascual Argente, Natàlia (Date of defense: 2021-10-22)
The objective of this work is the evaluation of the impact of new direct acting antivirals for Hepatitis C as a case of disruptive healthcare innovation that challenged healthcare systems. Two systematic ...
Costa Roger, Mar (Date of defense: 2021-05-14)
Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders, the etiology of which is unknown in the majority of cases. Little is known about complex genomic regions containing part of the ...
Signorelli, Camilo Miguel (Date of defense: 2021-06-11)
En el área de la neurociencia de la conciencia, actualmente existe una tendencia de contrastar y comparar modelos de conciencia. Aunque la palabra final es empírica, esfuerzos teóricos son esenciales ...
Leis Machín, Angela 1974- (Date of defense: 2021-03-18)
Mental disorders have become a major concern in public health, since they are one of the main causes of the overall disease burden worldwide. Depressive disorders are the most common mental illnesses, ...
Meseguer Donlo, Alberto (Date of defense: 2021-07-02)
Las células de nuestro cuerpo son capaces de tener comportamientos y morfologías completamente diferentes, pese a contener el mismo material genético. Entre los mecanismos que permiten esta diversidad ...
Sanllorente Melenchon, Albert (Date of defense: 2021-12-13)
Antecedents Les funcionalitats biològiques de les lipoproteïnes d’alta densitat (HDL) han sorgit com a marcadors alternatius als nivells de colesterol continguts en les HDL per explicar les capacitats ...
Abellán Écija, Alicia (Date of defense: 2021-10-04)
The high prevalence and burden of asthma and other chronic respiratory diseases worldwide has raised concerns about the potential role of environmental exposures. However, the evidence is still inadequate. ...
Laguillo Diego, Alejandra (Date of defense: 2021-03-12)
During cell division, microtubules (MTs) organize into a bipolar spindle that drives faithful chromosome segregation through the kinetochore fibers (k-fibers), bundles of parallel MTs that attach the ...
Karamtzioti, Paraskevi (Date of defense: 2021-02-01)
This thesis aimed to characterize the tubulin PTM profile of human oocytes and spermatozoa. Tubulin rich structures play critical roles in the cellular behavior of human gametes. Mutations in tubulin ...
575 - General genetics. General cytogenetics (20)
576 - Cellular and subcellular biology. Cytology (14)
615 - Pharmacology. Therapeutics. Toxicology (6)
616.6 - Pathology of the urogenital system. Urinary and sexual (genital) complaints. Urology (6)
577 - Material bases of life. Biochemistry. Molecular biology. Biophysics (5)