León Moreno, Theresa Elizabeth (Date of defense: 2013-10-30)
Nuclear receptor LXR is a ligand dependent transcription factor. The activating ligands of LXR are specific oxidized forms of cholesterol (oxysterols) and intermediate products of the cholesterol ...
Pereira Lopes, Selma Patrícia (Date of defense: 2014-02-20)
Trex1 is an exonuclease that was first identified in mammal cells and due to its role in DNA metabolism was conjectured to have a role in DNA damage repair and cancer. It was unexpected to find that ...
Bou Mira, Marta (Date of defense: 2016-02-04)
The aim of the present thesis is directed towards the comprehension of the mechanisms involved in the regulation of lipid and carbohydrate metabolism in relevant species in European aquaculture. Special ...
Marín Juez, Rubén (Date of defense: 2012-10-26)
The aim of this thesis was to study the function and regulation of two of the major players in the carbohydrate metabolism regulated by insulin, the facilitative glucose transporters GLUT2 and GLUT4, ...
Rius Radrigales, Mònica (Date of defense: 2014-10-30)
The aim of this work is to gain insight in the understanding of the biogenesis of membrane proteins, specially their folding, assembly and ER-exit. Our model is the human cystinuria transporter rBAT- ...
Martín Pérez, Miguel (Date of defense: 2012-10-25)
Stable isotopes, as tracers of the food chain, have been used to characterize the relationship between consumers and their food since isotopic fractionation implies discrimination against certain isotopes. ...
Bonacic, Kruno (Date of defense: 2016-02-26)
The main objective of this thesis was to evaluate the potential impacts of alternative VO–based feed formulations on the regulation of appetite and food intake in a commercial marine aquaculture species ...
Zare, Fatemeh (Date of defense: 2015-02-05)
Cancer immunotherapy represents a treatment strategy which is being clinically tested to complement surgery, radiotherapy and chemotherapy – the current cornerstones of our fight against cancer. It has ...
Zapater Cardona, Cinta (Date of defense: 2013-06-10)
In marine teleosts that spawn pelagic eggs (pelagophils), the process of oocyte hydration that occurs during meiosis resumption is a key physiological process for the survival of the eggs in the ocean. ...
Valverde Estrella, Lorena (Date of defense: 2015-02-06)
Aicardi-Goutières Syndrome (AGS) is a rare encephalopathy which mimics a viral intrauterine infection and is characterized by calcifications of the basal ganglia, cerebral atrophy and IFN-a in the ...