Secondary channel of the RNA polymerase, a target for transcriptional regulation in bacteria 

Fernández Coll, Llorenç (Date of defense: 2015-05-11)

Gene expression begins by an enzymatic complex known as RNA polymerase (RNApol). The basic unit (core) of RNApol in bacteria is formed by 5 protein subunits (α2ββ’ω). The three-dimensional structure of the RNApol defines ...