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Evolution, biogeography and systematics of the genus Cymbalaria Hill
Des de temps ancestrals la diversitat d’éssers vius del planeta ha fascinat i intrigat la humanitat. Com s’originen les espècies? Com han assolit la distribució geogràfica actual? En les darreres dècades, el gran avenç de ...
Evolution, diversification and ecology of a clade of strictly subterranean beetles (Troglocharinus, Family Leiodidae)
The general aim of this dissertation is to investigate the evolution, the diversification and some ecological traits of the species of the strictly subterranean genus Troglocharinus Reitter, 1908. The genus Troglocharinus ...
Evolutionary analysis of the genome load of loss-of-function variants and their contribution to immunodeficiencies
Human genomes have been found to harbor an unexpected number of ~100 loss-of-function (LoF) variants, with ~20 of them in an homozygous state, in most cases without a visible effect despite its potential truncation of ...
Evolutionary and functional patterns of the mandible and appendicular skeleton in Arvicola (Mammalia: Rodentia
Els estudis ontogenètics comparatius entre espècies filogenèticament properes amb diferents tipus de locomoció són essencials per comprendre en quina mesura la funció pot afectar les diferents etapes del desenvolupament ...
Evolutionary Bags of Space-Time Features for Human Analysis
The representation (or feature) learning has been an emerging concept in the last years, since it collects a set of techniques that are present in any theoretical or practical methodology referring to artificial intelligence. ...
Evolutionary dynamics of populations with genotype-phenotype map
In this thesis we develop a multi-scale model of the evolutionary dynamics of a population of cells, which accounts for the mapping between genotype and phenotype as determined by a model of the gene regulatory network. ...
Evolutionary dynamics of transcriptional and translational regulation in yeast
All living organisms respond to environmental stimuli by modulating the activity of different genes. This response can occur across many locations throughout the cell such as at the level of transcription, translation, and ...
Evolutionary ecology of range expansion in the colonizing plant Leontodon longirostris (Asteraceae)
L’interès per els processos eco-evolutius que determinen la capacitat d’expansió de la distribució de les espècies ha incrementat recentment com a conseqüència de l’increment de velocitat del canvi climàtic i global. Alguns ...
Evolutionary genetics of homo neanderthalensis :adaptive traits and methodological problems
The evolutionary history of H. neanderthalensis, interwoven with that of H. sapiens, has always fascinated the scientific world. Recent adavncess in paleogenetics shedds new light on the phylogenetic relationship between ...
Evolutionary genetics of malaria: genetic susceptibility and natural selection
Una de les forces selectives més fortes que han afectat a les poblacions humanes en la història més recent és el paràsit de la malària: Plasmodium falciparum, que és la causa de varis exemples d'adaptació induïda per ...
Evolutionary Genomics of Panarthropoda: Study of the chemosensory gene families across phyla and the radiation of the spider genus Dysdera (Araneae, Dysderidae) in the Canary Islands
[eng] During the last decade, advances in high-throughput sequencing (HTS) technologies have increased exponentially the generation of genomic data, especially of non-model species. In this thesis, we generated and used ...
Evolutionary history and drivers of diversification of the Mediterranean Nemesiidae spiders (Araneae, Mygalomorphae) = Història evolutiva i mecanismes de diversificació en aranyes mediterrànies de la familia Nemesiidae (Araneae, Mygalomorphae) = Historia evolutiva y mecanismos de diversificación en arañas mediterráneas de la familia Nemesiidae (Araneae, Mygalomorphae)
Mygalomorphs is a cosmopolitan group that inhabits all the continents except Antarctica. The group and has been commonly described as ‘primitive’ because of the retention of plesiomorphic characters, such as the presence ...
The evolutionary history of shearwaters: genomic analyses to resolve a radiation of pelagic seabrids
How populations differentiate and become new species is a foundational question to the field of evolutionary biology and has important implications for the generation of both local and global patterns of species-level ...
Evolutionary history of two Iberian Soricomorpha: genomics, phyligeography and dispersal patterns = Historia evolutiva de dos soricomorfos ibéricos genómica, filogeografía y patrones de dispersión
The study of intraspecific diversity is essential in ecology and evolution as they reveal fine-scale patterns and it is crucial in conservation planning. The main aim of this thesis is to study the evolutionary history of ...
Evolutionary insights into human DNA methylation
DNA methylation is a crucial epigenetic modification involved in numerous biological processes. However, despite its functional importance, the evolutionary history of this modification and the mechanisms diving such changes ...
Evolutionary insights into primate gene regulation and development of methods to study DNA modifications
Changes in the epigenetic regulation of gene expression have important implications for evolution. However, the study of these changes (i) has not been consistently assessed across closely related species, (ii) oftentimes ...
Evolutionary interplay between epigenetic regulation and gene expression dynamics in human and other primates
The evolution of the human phenotype involved gene regulatory innovations. Comparative functional epigenomic studies are a powerful tool with potential to shed light on many long-standing questions regarding human evolution. ...
Evolutionary patterns and processes of migratory behaviour in Palearctic-Paleotropical birds = Patrones y procesos evolutivos del comportamiento migratorio en aves del Paleártico-Paleotrópico
One of the most fascinating aspects of birds is their capability of migrate from one area to another throughout the year. Unravelling the patterns and processes involved in the evolution of migration is paramount to ...
Evolutionary patterns of the human skull. A quantitative genetic analysis of craniofacial phenotypic variation / Patrons evolutius del crani humà: Anàlisi geneticoquantitativa de la variacio fenotípica craniofacial.
This thesis is the final outcome of the project "Quantitative genetics of craniofacial traits: a functional approach to heritability", which received support from the Wenner-Gren Foundation for Anthropological Research in ...
Evolutionary recruitment and assembly of embryonic alternative splicing programs: insights form the Deuterostomia lineage
In the present work, we studied the evolution of alternative splicing (AS) from different perspectives. First, we performed a preliminary analysis where we identified alternative exons with tissue-specific regulation in ...
