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Characterization of polymers and Microencapsulated Phase Change Materials used for Thermal Energy Storage in buildings
The use of renewable heat decreases the consumption of fossil resources, although its usage is intermittent and usually does not match the demand. A proper thermal energy storage system design can eliminate this problem ...
Characterization of resistant Cucumis germplasm to manage root-knot nematodes Meloidogyne spp.
Plant resistance through grafting susceptible scions onto resistant rootstocks is an effective measure to supress root-knot nematode (RKN) populations and to reduce crop yield losses. However, the reiterative use of specific ...
Characterization of Rpn10 monoubiquitination as a novel way of proteasome regulation
Targeted protein degradation plays a central role in eukaryotic cell regulation and homeostasis. The ubiquitin proteasome system (UPS) is involved in a large number of cellular events, being, day by day, more difficult to ...
Characterization of s-oxidizing biomass through respirometric techniques under anoxic and aerobic conditions
La monitorització de l’activitat biològica en biofiltres percoladors és complexa ja que implica l’estimació de la concentració de biomassa i el rendiment de creixement. Aquestes dades no són senzilles de calcular quan ...
Characterization of seawater intrusion and submarine groundwater discharge in al luvial coastal aquifers: field and laboratory approach
Seawater intrusion (SWI) causes not only salinization of coastal aquifers, but also a reduction submarine groundwater discharge (SGD) and nutrient fluxes to marine ecosystems. We have developed a small scale experimental ...
Characterization of sexual commitment and the early steps of sexual development in the human malaria parasite Plasmodium falciparum
Transmission of malaria requires that some parasites abandon asexual replication and develop into sexual stages termed gametocytes. The discovery of the transcription factor PfAP2-G as the master regulator of sexual ...
Characterization of SF3B1 mutation in chronic lymphocytic leukemia and the role of new splicing modulators
Mutations in Splicing Factor 3b Subunit 1(SF3B1) are observed in 15% of patients with chronic lymphocytic leukemia (CLL) and are associated with worse disease prognosis. SF3B1 is involved in pre-mRNA splicing and is the ...
Characterization of simple and complex genomic structural variation : a study of human populations and leukaemia
Over the last ten years, improvements in molecular techniques and the arrival of the next-generation sequencing technologies have revealed a large amount of structural variation (SV) in the human genome. Consequently, there ...
Characterization of snail1 and pten transcriptional regulation by snail1: New insights into epithelial-to-mesenchymal transition and cell resistance to apoptosis
The product of the snail1 gene (SNAIL1) is a transcriptional repressor required for triggering the epithelial-to-mesenchymal transition (EMT). SNAIL1 transcription is induced when epithelial cells are forced to acquire a ...
Characterization of Spatial Heterogeneity in Groundwater Applications
La heterogeneidad es una característica saliente de cada formación geológica natural. En las últimas décadas un gran número de trabajos se han centrado en estudiar la influencia de la heterogeneidad en los problemas de ...
Characterization of synthetic lethality between MYC activation and splicing inhibition in an immortalized cell line : roles of alternative splicing
Cancer cells exhibit a synthetic lethal (SL) phenotype when Myc upregulation is combined with antitumor drugs targeting the splicing factor SF3B1. However, the molecular events and mechanisms responsible for this vulnerability ...
Characterization of the 5-HT(7) receptor as a new therapeutic target for the treatment of pain
The work showed in this Thesis has been part of the “5-HT7 and neuropathic pain” project in the pharmaceutical company Esteve. Thus, the aim of this Thesis was in line with the goal of the 5-HT7 project at Esteve, focused ...
Characterization of the Armcx/Almc10 gene family function in mitochondrial dynamics and neural development
The Armcx gene cluster arose by retrotransposition from a single Arm-containing gene (Armc10), and by subsequent short-range tandem duplications of a rapidly evolving region of the Eutherian X chromosome. In this work we ...
Characterization of the biological effects of natural compounds against inflammation, metabolic syndrome and cancer
Els productes naturals han sigut àmpliament utilitzats per al tractament i prevenció de moltes malalties. L’objectiu principal d’aquesta tesi ha estat caracteritzar compostos naturals bioactius que podrien ser utilitzats ...
Characterization of the circadian clock function in the control of cell cycle progression to modulate growth in Arabidopsis thaliana
La función circadiana es esencial para el crecimiento y adaptación de las plantas a su entorno. La maquinaria molecular responsable de la generación de ritmos circadianos está basada en la expresión rítmica de genes cuyo ...
Characterization of the DNA methylation patterns of chemosensitive and chemoresistant human cancer cells: Biological and clinical impact
Although chemotherapeutic drugs are widely used in order to improve the cancer outcome, drug resistance remain the most unpredictable factor affecting chemotherapy and a major impediment to successful patient’s treatment. ...
Characterization of the enzymes involved in the diolsynthase pathway in Pseudomonas aeruginosa
In 2015 our research group described, in P. aeruginosa, the oleate-diol synthase system which consists of two sequentially and independently enzymatic reactions: 10S-Dioxygenase (10-DOX) (PA2077) used oleic acid (as preferred ...
Characterization of the fas death receptor antagonist in the nervous system, lifeguard (LFG)
La activación del Receptor de Muerte Fas, también llamado APO-1 o CD95, da lugar a la formación del Death Inducing Signaling Complex (DISC). Este complejo proteico contiene FADD y caspasa-8, entre otras proteínas, y causa ...
Characterization of the functional connection between the BROMODOMAIN and EXTRATERMINAL DOMAIN PROTEIN 9 (BET9) and the circadian clock in Arabidopsis thaliana
The circadian clock is an endogenously generated timekeeping mechanism that generates 24-hour rhythms in multiple biological processes. The rhythmic oscillations provide an adaptive advantage, allowing organisms to anticipate ...
Characterization of the Hox patterning genes in acoel flatworms
One of the main issues in animal evolution deal with the transition from radial organisms (Cnidaria and Ctnenophora), with only one axis of symmetry, the Oral-Aboral (OA) axis, to bilateral organism (Bilateria), bearing ...
