Ara mostrant els elements 11-18 de 18
Postma, Tobias Maria (Data de defensa: 2014-03-21)
Cysteine (Cys) is a unique amino acid due to its ability to form reversible covalent disulfide bonds. These bonds cause conformational constraints which make peptides or proteins more rigid and stable. ...
Zamudio Vázquez, Rubí (Data de defensa: 2014-02-14)
Triostins are members of the quinoxaline antibiotic family, together with the "prototypical bisintercalator" echinomycin. These molecules display interesting antitumour activities as they inhibit ...
Pelay Gimeno, Marta (Data de defensa: 2013-02-15)
Pipecolidepsin A is a cyclodepsipeptide produced by a Homophymia marine sponge that has shown interesting anticancer properties against several human cancer cell lines. From a structural point of view, ...
Góngora Benítez, Miriam (Data de defensa: 2013-02-08)
Synthesis of Cys-containing peptides has long been posed as an attractive challenge for peptide chemist. Protecting groups for the nucleophilic beta-thiol group of Cys residues must be stable during ...
Gil Escolano, Alejandro (Data de defensa: 2018-02-16)
Marine natural products (MNPs) are, undoubtedly, highly valuable starting points for drug-development programs. Generally, MNPs show a well-defined spatial orientation that have evolved for thousands ...
Mas Moruno, Carlos (Data de defensa: 2009-03-05)
La sepsis es un síndrome muy complejo de definir, diagnosticar y tratar. La patología de la sepsis se deriva de una respuesta perjudicial del organismo a una infección. La exposición a endotoxinas ...
Herraiz Cobo, Jesús (Data de defensa: 2017-07-13)
Mayotlide is a marine peptide isolated by PharmaMar S.A. from Spongia sp.. The sequence of the aminoacids were achieved by MS-MS spectrometry, where two of them were tryptophans. The NMR spectroscopy ...
Ramos Tomillero, Iván (Data de defensa: 2016-07-15)
Cancer is a heterogeneous disease that represents one of the principal causes of mortality in developed countries. Due to the social and economic implications of this pathology, tremendous efforts have ...