Pecoraro, Matteo (Date of defense: 2014-10-02)
La senescencia celular es una detención irreversible del ciclo celular que tiene lugar en respuesta a diversos estímulos de estrés, actuando como un mecanismo supresor de tumores para impedir la ...
Storer, Mekayla (Date of defense: 2014-12-18)
Cellular senescence is an irreversible form of proliferative arrest, historically linked to tumour suppression and aging. Recent discoveries, however, have extended its known role to include complex ...
Ritschka, Birgit (Date of defense: 2017-09-15)
Cellular senescence has mainly been associated with tumor suppression and aging, mediated through cell intrinsic cell-cycle inhibition and arrest. However, through secretion of specific proteins, termed ...
Di Giacomo, Valeria (Date of defense: 2014-12-12)
P63 is a transcription factor of the p53 family with key roles in embryonic development, stem cells and cancer. P63-deficient mice fail to form stratified and glandular epithelia, including the prostate, ...