Herrero Vicente, Jorge (Date of defense: 2024-02-26)
Cancer cells exhibit a synthetic lethal (SL) phenotype when Myc upregulation is combined with antitumor drugs targeting the splicing factor SF3B1. However, the molecular events and mechanisms responsible ...
Domínguez Rodríguez, Diana (Date of defense: 2021-05-04)
La metàstasis és responsable del 90% de les morts per càncer, demostrant l’existent manca de coneixement en relació als seus mecanismes moleculars. Investigacions anteriors del nostre laboratori han ...
Sondermann, Nathalie Allegra Faye (Date of defense: 2024-03-21)
Polycomb repressive complexes (PRC1/2) are key chromatin regulators in development. Their deregulation is implicated in various cancers including leukaemia. Meanwhile, MLL-rearrangements by chromosomal ...