Palacio Lacambra, María Eugenia (Date of defense: 2018-12-20)
L'estimació de la funció renal ha de ser el més precisa possible per ajustar correctament la dosi dels fàrmacs, especialment els que s'eliminen via renal com el ganciclovir. Les equacions CKD-EPI i MDRD ...
Yoldi, Guillermo (Date of defense: 2018-10-23)
The discovery that RANK signaling mediates the protumorigenic role of progesterone in the mammary gland and its association with poor prognosis in breast cancer has opened the possibility of using RANKL ...
Hurtado Barroso, Sara (Date of defense: 2019-10-28)
La dieta mediterránea, rica en hortalizas y frutas, tiene efectos beneficiosos en la salud debido en parte a su alto contenido en fitoquímicos biológicamente activos, entre ellos los carotenoides y los ...
Rosell Oliveras, Mireia (Date of defense: 2020-12-21)
The study of the 3D structural details of protein interactions is essential to understand biomolecular functions at the molecular level. In this context, the limited availability of experimental structures ...
Ugarteburu López, Olatz (Date of defense: 2021-09-30)
Las enfermedades del metabolismo energético mitocondrial son un grupo de patologías con una gran heterogeneidad clínica, bioquímica y genética. Aunque en la última década la implementación de las técnicas ...
Nicolàs i Aragó, Adrià (Date of defense: 2022-12-14)
[eng] L-type amino acid transporters play key roles in human physiology and are involved in several human pathologies such as primary inherited aminoacidurias (Feliubadaló et al., 1999; Torrents et al., ...
González Velasco, Lorena (Date of defense: 2021-09-14)
Non-canonical activation of p38α MAPK has been associated to cardiomyocyte death in several cardiovascular pathologies, such as myocardial ischaemia-reper- fusion injury. Unfortunately, current p38α ...
García Lema, Jorge (Date of defense: 2020-10-08)
Adenosine deaminase acting on tRNAs (ADAT) is a eukaryotic heterodimer, composed by ADAT2 and ADAT3, that catalyses the deamination of adenosine-to-inosine in the anticodon loop of tRNAs. ADAT proteins ...
Sanchis Villariz, Ana (Date of defense: 2018-07-25)
The central topic of this thesis has been the study, development and validation of diverse multiplexed diagnostics platforms and techniques that can be applied to a wide range of topics, from environmental ...
Carvajal Vidal, Paulina Andrea (Date of defense: 2021-02-19)
Existe una amplia variedad de alternativas terapéuticas para el tratamiento de las enfermedades inflamatorias dérmicas que permiten una aproximación local o sistémica dependiendo de la severidad de los ...