Mostrando ítems 1-10 de 18
Cánovas Bilbao, Begoña (Fecha de defensa: 2017-07-20)
In normal epithelial cells, p38α has a well-established role as a tumor suppressor. However, recent reports have illustrated pro-tumorigenic functions for the p38α pathway by promoting tumor cell survival ...
Román González, Lidia (Fecha de defensa: 2014-01-31)
Within the hematopoietic system, all mature blood cells are generated. Every differentiation step is characterized by the activation of a new, lineage specific, genetic program and the extinction of the ...
Bassani, Nicklas (Fecha de defensa: 2017-12-15)
Antiangiogenic drugs are used clinically for treatment of different types of cancers and in the case of renal cell carcinoma (RCC) are now standard first-line treatments (Rini, 2009). Nevertheless, these ...
Luscieti, Sara (Fecha de defensa: 2016-11-22)
Iron is an essential micronutrient required for many cellular reactions and a tight regulation of its metabolism is therefore crucial for health. Cellular iron homeostasis relies on the coordination of ...
Sala Hojman, Ada (Fecha de defensa: 2016-07-15)
LIF is a pleiotropic cytokine that can act as an immunomodulatory factor in different biological processes, such as embryo implantation, organ transplantation tolerance and multiple sclerosis. Here, we ...
Peixoto, Francisca de Oliveira (Fecha de defensa: 2017-09-05)
The correct timing of adult stem cell function is essential for tissue homeostasis. Our group was among the first to show that circadian rhythms segregate important stem cell functions along the day. ...
Bazzocco, Sarah (Fecha de defensa: 2016-01-27)
Colorectal cancer is a disease caused by genetic and epigenetic changes. Inactivation of tumor suppressor genes and activation of oncogenes are key landmarks in tumor progression. However, the list of ...
Bernadó Morales, Cristina (Fecha de defensa: 2015-04-23)
In response to oncogenic stresses cells activate two different tumor suppressor mechanisms: Oncogene-induced senescence (OIS), a terminal cell proliferation arrest, or oncogene-induced apoptosis (OIA), ...
Bonastre Llort, Ester (Fecha de defensa: 2014-10-30)
El càncer de pulmó afecta 1,6 milions de persones a tot el món, i és la primera causa de mort per càncer. El promig de l’índex de supervivència als 5 anys per tots els càncers està al voltant del 50%, ...
Gómez Miragaya, Jorge (Fecha de defensa: 2018-04-27)
Chemotherapy is a general treatment for most breast tumors and depending on breast cancer subtype combination with targeted anti-hormonal or anti-HER2 therapy is conducted. Taxane-based regimens constitute ...