Browsing by Title

Study of the characterization of the mechanical properties of materials with elastomeric behavior for biomedical applications

Adrover Monserrat, Bàrbara (Date of defense: 2023-02-24)

(English) The mechanical characterization of new materials used in the Material Extrusion technique (MEX) in 3D printing is essential. The use of this technique is growing and with it the possible applications of printed ...

Study of the components and adherence to the Mediterranean diet on functional and cognitive ageing: from dietary assessment to a metabolomic approach

Tor Roca, Alba (Date of defense: 2023-12-20)

[eng] Healthy dietary patterns, such as the Mediterranean diet, have been linked to reduced chronic disease risk and mortality. However, the evidence regarding the impact of healthy dietary patterns on physical and cognitive ...

Study of the components that determine the applicability of pathogenicity predictors in the clinical setting

Aguirre Gómez, Josu (Date of defense: 2020-07-14)

The translation of Next Generation Sequencing (NGS) technologies from the research field to the clinical setting and, specifically, the results obtained in terms of diagnostic yield remain far from expected. This situation ...

Study of the conformational dynamics of prolyl oligopeptidase

López Asamar, Abraham (Date of defense: 2015-07-17)

Prolyl oligopeptidase (POP) is an 81-KDa bidomain enzyme which hydrolyses short proline-containing peptides. This enzyme is involved in mnemonic and cognitive processes, and the dysregulation of POP activity is related to ...

Study of the contribution of ORMDL3 to the cannabinoid antitumoral action

García López, Roberto (Date of defense: 2018-04-06)

Genome-wide association studies have been very useful tools in the last years to relate genes and diseases. Thereby, single nucleotide polymorphisms have been linked to increased ORMDL3 expression and to different pathologies ...

Study of the cooperative effect of UVR, BRAF and LKB1 in melanoma

González Sánchez, Elena (Date of defense: 2019-06-14)

Entender los mecanismos moleculares relacionados con la melanomagénesis es clave a la hora de encontrar nuevas estrategias preventivas y terapéuticas contra esta letal enfermedad. La epidemiología indica que hay factores ...

Study of the crosstalk between microglia and oligodendrocyte-related cells in central nervous system myelination through interactomics

Enrich Bengoa, Jennifer (Date of defense: 2022-12-20)

Els trastorns desmielinitzants com l’esclerosi múltiple (EM) es caracteritzen per la destrucció de la mielina i el deteriorament de la remielinització a causa de fallades en la diferenciació de les cèl·lules progenitores ...

Study of the cytotoxic activity and immunogenicity of the differentiated morphotypes of the genus Mycobacterium, in relation with their cell wall composition

Llorens Fons, Marta (Date of defense: 2018-03-22)

Mycobacterium és un gènere de microorganismes que compren importants patògens de la humanitat, com l’agent etiològic de la tuberculosis, Mycobacterium tuberculosis. Moltes espècies de micobacteris presenten dos morfotips ...

Study of the diffusive properties of extracellular matrix gels used in 3D cultures

Galgoczy, Roland (Date of defense: 2013-12-03)

The extracellular matrix (ECM) hinders diffusion in both tissues and hydrogels used in 3D cultures. However, how geometric and non-geometric ECM properties contribute to diffusion hindrance remains poorly understood. To ...

Study of the disassembling of the nucleus induced by gossypol in apoptotic nuclear fragmentation-deficient human glioblastoma cells

Martínez Escardó, Laura (Date of defense: 2020-10-02)

L’apoptosi, una forma de mort cel·lular regulada, es caracteritza per una cadena d’esdeveniments bioquímics i morfològics orquestrats per una família de proteases anomenades caspases. La posada en marxa de les caspases ...

Study of the dynamic behavior of Pelton Turbines

Egusquiza Montagut, Mònica (Date of defense: 2020-02-14)

The future of hydropower is tied to the rapid increase of new renewable energies, such as photovoltaic and wind energy. With the growing share of intermittent electricity production, the operation of hydropower installations ...

Study of the effect of process parameters on the thermophilic anaerobic digestion of sewage sludge, evaluation of a thermal sludge pre-treatment and overall energetic assessment

Ferrer i Martí, Ivet (Date of defense: 2008-10-08)

El consum energètic representa un 30 % dels costos d'operació en sistemes intensius de tractament d'aigües residuals urbanes. En depuradores convencionals que utilitzin un sistema de fangs activats, entorn al 15-20 % de ...

Study of the Electron-Transfer properties of phenolics and their relationship with the biological activity on cancer cells

Carreras Cardona, Anna (Date of defense: 2012-05-04)

During aerobic cell metabolism, molecular oxygen is reduced to water through electron-transfer reactions, and the oxygen not completely reduced is transformed into a set of neutral and free radical molecules with high ...

Study of the exfoliation process in epoxy-clay nanocomposites

Shiravand, Fatemeh (Date of defense: 2014-06-03)

Cured epoxy resins are highly cross-linked polymers which are increasingly important in high performance engineering field due to the stiffness, high strength, heat resistance and solvent resistance. However one major ...

Study of the expression and regulation of the autocrine loop components of the cyclooxygenase pathway and their implication in aspirin exacerbated respiratory disease

Machado de Carvalho, Liliana Sofia (Date of defense: 2015-11-27)

Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by the combination of nasal polyps (NPs), chronic hypertrophic eosinophilic sinusitis, asthma and severity to any medication that inhibits ...