Now showing items 2817-2836 of 3222

    Symmetries in constraint satisfaction: Weisfeiler-Leman invariance and promise problems 

    Butti, Silvia (Date of defense: 2022-10-20)

    This thesis focuses on the complexity of the fixed-template Constraint Satisfaction Problem (CSP) and its variants. Our contributions are two-fold. On the one hand, we study how closure of the space of CSP instances under ...

    Synthesis of fatty acid derivatives of catechol compounds that exhibit negative modulation of food intake and antioxidant properties 

    Almeida Cotrim, Bruno (Date of defense: 2011-01-10)

    Obesity constitutes a problem whose manifestations have consequences in almost every field of the medicine and nowadays there is a lack of pharmacological therapy alternatives for its long term treatment. Lipidic compounds ...

    Synthetic biology in Mycoplasma pneumoniae 

    Paetzold, Bernhard (Date of defense: 2013-12-02)

    M. pneumoniae is one of the smallest self-replicating organisms. Many organism wide studies have been performed on M. pneumoniae and provide a wealth of information on the bacteria. However, the genetic tools to manipulate ...

    Synthetic view of retail spaces using camera and RFID sensors on a robot 

    Nur, Kamruddin Md. (Date of defense: 2016-01-11)

    In this thesis, two approaches of information presentation on indoor view have been presented using Radio-Frequency Identification (RFID) and camera sensors on a robot. The goal is to capture images of the indoor environment ...

    System-level performance of interference-aware spatial frequency reuse 

    Mungara, Ratheesh Kumar (Date of defense: 2016-12-01)

    Spatial frequency reuse is a long-established approach for enhancing the capacity of wireless systems through increased spectral efficiency (bits per second per unit bandwidth). The future 5th generation of wireless systems ...

    Systematic and quantitative analysis of the early embryonic development of Caenorhabditis elegans 

    Krüger, Angela (Date of defense: 2012-12-14)

    The embryo of Caenorhabditis elegans is a model system in which development can be studied at single cell resolution. In this thesis I describe the use of a semi-automatic nuclear tracking algorithm to analyze cellular ...

    Systematic functional analyses of spliceosomal components reveal novel mechanisme of alternative splicing regulation 

    Tejedor Vaquero, Juan Ramón (Date of defense: 2014-06-11)

    Alternative splicing is an essential regulatory layer of gene expression that expands the coding potential of the genome in multicellular organisms. The spliceosome -the sophisticated machinery involved in intron removal- ...

    Systemic effects of chromosomal instability induced tumorigenesis : A role of JAK/STAT and cytokine secretion in coupling inflammation to maturation defects in Drosophila 

    Romão, Daniela (Date of defense: 2021-09-10)

    Alterations in developmental transitions are common among animals to compensate for growth disturbances. These variations are usually a consequence of altered steroidal hormone production resulting in puberty delays. ...

    Systemic risk in the banking sector: a network perspective 

    Hans, Christina (Date of defense: 2017-09-26)

    This thesis investigates various aspects of systemic risk in nancial networks. Chapter 1 explores the existence of a contagion channel to security returns given that banks are connected via overlapping portfolios. Making ...

    Systems and synthetic biology studies in Saccharomyces cerevisiae 

    Regot Rodríguez de Mier, Sergi (Date of defense: 2011-07-15)

    A fundamental property of living cells is the ability to sense and respond appropriately to changing environmental conditions. In budding yeast (Sacharomyces cerevisiae), changes in extracellular osmotic conditions are ...

    Tag recommendation using folksonomy information for online sound sharing platforms 

    Font Corbera, Frederic (Date of defense: 2015-06-11)

    Les plataformes d'intercanvi de recursos multimèdia contenen grans quantitats de contingut creat pels seus usuaris. Habitualment, aquest contingut no està ben anotat. En aquesta tesi, proposem mètodes per ajudar els ...

    Tailoring dependency models to NLP tasks 

    Kolz, Benjamin (Date of defense: 2016-04-22)

    Currently available dependency structures differ significantly in the linguistic criteria they are based on, but are not always adequate for their later use in natural language processing tasks. This dissertation analyses ...

    Tan lejos, tan cerca: la traducción y circulación de literatura latinoamericana en China 

    Chen, Yehua (Date of defense: 2020-01-28)

    Esta tesis investiga los criterios y mecanismos aplicados para la selección textual en la traducción de la literatura latinoamericana al chino y la imagen sobre América Latina que se ha construido por su producción literaria, ...

    Tandem repeat variation in human and great ape populations and its impact on gene expression divergence 

    Carvalho, Tiago Loureiro de (Date of defense: 2016-01-21)

    Genetic variation in humans and the great apes has been amply explored using a wide variety of markers, among them tandem repeats (TRs). Because of the nature of TRs, highly variable in length due to its high mutation rate, ...

    TANGO1 asembles a machine for collagen folding and export 

    Ashok, Anupama (Date of defense: 2019-01-21)

    COPII vesicles of 60-90nm diameter are known to export secretory cargoes from endoplasmic reticulum (ER). However, they cannot be employed to export bulky cargoes like the collagens that can reach up to 400 nm in length. ...

    Targeting aging and Alzheimer's disease : from GM1 ganglioside to amyloide-β peptide 

    Valls Comamala, Victòria (Date of defense: 2018-09-07)

    Aging is the main challenge that humanity will face on the near future. Brain aging is associated with cognitive deficiencies and is the main risk factor for Alzheimer’s Disease (AD). AD is the most common neurodegenerative ...

    Targeting BRAF mutant pre-mRNA alternative splicing in melanoma 

    Aya Moreno, Francisco (Date of defense: 2023-02-15)

    Alternative splicing of BRAF mRNA can provide a resistance mechanism to BRAF and MEK inhibitors that has been described mostly in BRAF-mutant melanoma. The mechanisms underlying the production of a variety of BRAF mRNA ...

    Targeting endogenous analgesia systems for endometriosis treatment 

    Escudero Lara, Alejandra (Date of defense: 2021-05-06)

    Endometriosis is a chronic inflammatory disease that affects 1 in 10 women of childbearing age. It is characterized by the growth of endometrium in extrauterine locations and is associated with chronic pelvic pain, ...

    Targeting glial cells as a therapeutic approach for the treatment of chemotherapy-induced neuropathic pain 

    Piedra Barrull, Sheila (Date of defense: 2022-01-25)

    Chemotherapy-induced peripheral neuropathy (CIPN) is the most common adverse effect of many first-line antineoplastic agents, which negatively affects the quality of life and clinical outcome. Current clinical management ...

    Targeting the endocannabinoid system for therapeutic purposes 

    Busquets Garcia, Arnau (Date of defense: 2013-07-04)

    The endocannabinoid system is an endogenous neuromodulatory system that regulates a plethora of physiological functions, including the modulation of memory, anxiety, pain, synaptic plasticity and neuronal excitability, ...