Regulation of NUMB alternative splicing by RBM10 and control of cancer cell proliferation 

Hernández Ribera, Jordi (Date of defense: 2016-11-23)

Alternative pre-mRNA splicing of the Notch regulator NUMB exon 9 switches between isoforms that promote (exon inclusion) or prevent (exon skipping) cell proliferation. We have studied NUMB alternative splicing regulation ...