Methyltransferase inhibitors interfere with Snail1 action on myofibroblast activity to prevent fibrosis and metastasis 

Sala Romanyà, Laura (Date of defense: 2018-06-20)

Snail1 is a transcription factor which activity is required for the fibroblasts-to-myofibroblast differentiation. In the first part of the thesis we characterize a protein complex involving Snail1, PRMT1 and PRMT4, two ...