Mostrando ítems 111-120 de 149
Palomar Cros, Anna (Fecha de defensa: 2022-11-02)
Les malalties no transmissibles (MNT) causen cada any 41 milions de morts en tot el món. Arran del descobriment del rellotge circadiari i dels efectes nocius del treball de nit continuat, s'ha enfocat ...
Roewenstrunk, Julia Maria (Fecha de defensa: 2016-12-19)
Gene dosage alterations of the kinase DYRK1A are linked to disease in humans. To better understand DYRK1A activities an interactome analysis was performed. RNF169, an E3-ubiquitin ligase key component ...
Hernández Ribera, Jordi (Fecha de defensa: 2016-11-23)
Alternative pre-mRNA splicing of the Notch regulator NUMB exon 9 switches between isoforms that promote (exon inclusion) or prevent (exon skipping) cell proliferation. We have studied NUMB alternative ...
Doerr, Stefan (Fecha de defensa: 2016-09-16)
Molecular dynamics has established itself over the last years as a strong tool for structure-based molecular investigation in biology. Stefan Doerr's thesis concerns the application of machine learning ...
Vigevani, Luisa (Fecha de defensa: 2016-11-21)
RNA splicing is the process of removal of introns from pre-mRNAs. It is carried out by the spliceosome, composed of five small nuclear ribonucleoproteins (snRNPs). Several small molecules with antitumor ...
Regot Rodríguez de Mier, Sergi (Fecha de defensa: 2011-07-15)
A fundamental property of living cells is the ability to sense and respond appropriately to changing environmental conditions. In budding yeast (Sacharomyces cerevisiae), changes in extracellular osmotic ...
Ní Chárthaigh, Róisín-Ana (Fecha de defensa: 2020-07-03)
RNA-binding proteins are potent regulators of post-transcriptional gene expression. Among the repertoire of RNAs bound by a particular RNA-binding protein, networks of co-ordinately regulated RNAs, or ...
Kemena, Carsten (Fecha de defensa: 2012-12-12)
Sequence alignment is one of the basic methods to compare biological sequences and the cornerstone of a wide range of different analyses. Due to this privileged position at the beginning of many studies ...
Viéitez Manrique, Cristina (Fecha de defensa: 2014-12-18)
In response to fluctuations in the environment, all living organisms have the ability to sense, respond and adapt to the new conditions. In budding yeast (Saccharomyces cerevisiae) there is a massive ...
Poglayen, Daniel (Fecha de defensa: 2016-01-28)
Cellular behaviour is regulated by a very precise system in which the complex interplay between various types of biomolecules plays a crucial role for the proper functioning of the system itself. Proteins ...