Jiménez-Castells, Carmen (Date of defense: 2010-12-20)
Carbohydrate-binding proteins of non-immunological origin -lectins- have been recognized over the last decades as decisive players in numerous biological processes, ranging from cellcell communication, ...
Martínez Høyer, Sergio (Date of defense: 2012-10-11)
The calcineurin-NFATc signaling pathway is involved in many aspects of the development and function of the immune, neural, skeletal, cardiovascular and muscular system of vertebrates. Regulators ...
Delli Ponti, Riccardo (Date of defense: 2019-01-16)
The secondary structure of an RNA molecule is fundamental for its function. However, structural conservation and the structure of RNA in vivo are still poorly understood. Data from recent high-throughput ...
Cid Samper, Fernando (Date of defense: 2020-01-27)
Ribonucleoprotein granules (RNP granules) are liquid-liquid phase separated complexes composed mainly by proteins and RNA. They are responsible of many processes involved in RNA regulation. Alterations ...
Aragón Manresa, Ferran (Date of defense: 2008-07-16)
Durant els primers estadis del desenvolupament embrionari dels metazous els teixits embrionaris son progressivament regionalitzats fins que adquireixen destins específics. En els vertebrats, el tub ...
Barrero Asencio, Mercedes (Date of defense: 2023-03-02)
During reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), the epigenome needs to be reset. A prime example of this is the reversal of the silent state of the inactive X chromosome ...
Fernández Mariño, Ana Isabel (Date of defense: 2013-07-29)
The large-conductance Ca2+- and voltage-gated K+ (BK) channel containing the pore-forming and the regulatory B1 subunits play a pivotal role in the control of arterial tone and modification of channel ...
Durán Alcaide, Ángel (Date of defense: 2010-03-04)
The work of this thesis was focused on the development of high-performance algorithms for a new generation of molecular descriptors, with many advantages with respect to its predecessors, suitable for ...
Sala Romanyà, Laura (Date of defense: 2018-06-20)
Snail1 is a transcription factor which activity is required for the fibroblasts-to-myofibroblast differentiation. In the first part of the thesis we characterize a protein complex involving Snail1, PRMT1 ...
Mansouri, Leila (Date of defense: 2023-03-27)
El continuo aumento de los proyectos de producción de datos genómicos a gran escala, como el "Earth BioGenome Project" (Lewin et al., 2018), pone los métodos de análisis de datos bajo una presión sin ...