Prieto Barja, Pablo (Date of defense: 2017-01-12)
In this PhD I have used NGS technologies in different organisms and scenarios such as in ENCODE, comparing the conservation and evolution of long non-coding RNA sequences between human and mouse, using ...
Plass Pórtulas, Mireya (Date of defense: 2011-07-12)
L’splicing és el mecanisme pel qual els introns són eliminats del pre-mRNA per generar un trànscrit madur. Aquest procés és dut a terme per un complex macromolecular anomenat spliceosoma i requereix el ...
Pittis, Alexandros (Date of defense: 2016-10-14)
The origin of eukaryotic compartmentalization stands as a major conundrum in biology. Current evidence indicates that the last eukaryotic common ancestor (LECA) already possessed many eukaryotic hallmarks, ...
Carvalho, Tiago Loureiro de (Date of defense: 2016-01-21)
Genetic variation in humans and the great apes has been amply explored using a wide variety of markers, among them tandem repeats (TRs). Because of the nature of TRs, highly variable in length due to ...
López Valenzuela, María (Date of defense: 2015-01-15)
MicroRNAs (miRNAs) are major contributors to phenotypic diversity and have a demonstrated role in evolution. We performed an analysis on how miRNA nucleotide substitutions may have contributed to human ...
Verd Fernández, Berta (Date of defense: 2016-01-21)
During insect development segments either form sequentially (short-germband) or simultaneously (long-germband) . The gap genes comprise the first zygotic regulatory layer of the segmentation gene ...
Mondal, Mayukh (Date of defense: 2016-11-21)
Human genome project published their first human whole genome sequence on 2001 at the cost of billions of dollars. Since, the cost of sequencing is decreasing faster than Moore’s law. Now, we not only ...
Garriga i Rigau, Damià (Date of defense: 2010-01-21)
La malaltia de la bursitis infecciosa, o alaltia de Gumboro, és una patologia aviària d'origen viral que afecta principalment les cries d'aus. En les granges de cria d'aviram, el virus que la origina, ...
Burga Ramos, Alejandro Raúl (Date of defense: 2012-07-20)
Genetically identical cells and organisms growing in homogenous environmental conditions can show significant phenotypic variation. Furthermore, mutations often have consequences that vary among individuals ...
Bello, Carla (Date of defense: 2017-12-15)
La identificación de elementos funcionales en el genoma no-codificante continúa siendo una tarea desafiante. La genómica comparativa puede ayudarnos a entender como estos elementos han evolucionado y ...