Simonte, Giacoma (Date of defense: 2016-12-14)
My PhD project was focused on understanding if endogenous bone-marrow cells (BMCs) could participate in the repair of mouse retina following N-Methyl-D-aspartate (NMDA) damage. We wanted to explore the ...
Martinez Sarmiento, Jose Angel (Date of defense: 2023-05-04)
Elucidating the mechanism of somatic cell reprogramming has been hampered by the limitations of iPSC systems to uncover the correctly reprogramming cells. Here, by using the highly efficient heterokaryon ...
Cortés Albarracín, Paola Andrea (Date of defense: 2019-12-02)
Mouse embryonic stem cells (ESCs) require extracellular signals to induce the expression of intrinsic core pluripotency factors: Oct4, Sox2 and Nanog, known as the OSN triad. Notably, the Wnt/β-catenin ...
Martín de Dios, Laura (Date of defense: 2024-05-06)
La organización del genoma en células mamíferas sigue siendo en gran parte desconocida. Un nivel fundamental de organización se considera el bucle de cromatina, que consiste en una región de ADN atrapada ...