Stankeviciute, Laura (Date of defense: 2023-12-12)
This Thesis delves into the intricate relationship between sleep disruptions and Alzheimer's disease (AD). Sleep disturbances are a prevalent feature of AD, and evidence suggests they may accelerate ...
La Porta, Carmen (Date of defense: 2015-10-15)
Chronic pain is a major clinical problem producing huge economic and social burdens. Currently, chronic pain treatment has limited efficacy and significant side effects. One of the reasons of this unmet ...
Marchese, Domenica (Date of defense: 2016-11-14)
The role of RNA processing in the pathogenesis of neurodegenerative diseases is still poorly understood. α-synuclein (SNCA) is a presynaptic neuronal protein known as the major component of Lewy bodies, ...
Malhotra, Sunny (Date of defense: 2014-01-15)
The aim of the thesis was to identify biomarkers for multiple sclerosis (MS) prognosis, in particular disease activity biomarkers and interferon-β (IFNβ) treatment response biomarkers. The results presented ...
Bañón González, Aitor (Date of defense: 2023-02-24)
The statoacoustic ganglion (SAG) is a complex 3D structure composed by neurons in charge of transmitting the information from inner ear hair cells to the CNS. During development, SAG copes with otic ...
Radó i Trilla, Núria (Date of defense: 2013-05-03)
In this thesis we aimed to study evolutionary implications of low-complexity regions, protein sequences of very simple amino acid composition. Its uncontrolled expansion causes several human diseases, ...
Júlvez Calvo, Jordi (Date of defense: 2007-09-27)
Antecedents: No hi ha gaire coneixement sobre el neurodesenvolupament de preescolars i la seva susceptibilitat enfront a factors ambientals. <br/>Objectius: Avaluar les respostes del neurodesenvolupament ...
Godoy Zeballos, Juan Alejandro (Date of defense: 2018-06-29)
Las mitocondrias y su función metabólica cambian con el envejecimiento y pueden ser el factor más importante en el desarrollo de diferentes enfermedades neurodegenerativas relacionadas con la edad, ...
Coma Camprodón, Mireia (Date of defense: 2007-06-08)
En aquest treball de tesis doctoral s'estudia el paper de l'estrès oxidatiu tant a la etiologia com a la patofisiologia del dany vascular associat a la malaltia d'Alzheimer. Es demostra la capacitat de ...
Pujol Martí, Jesús (Date of defense: 2012-03-02)
Les neurones sensorials projecten al sistema nerviós central seguint una distribució espacial ordenada, formant mapes neuronals que representen propietats dels estímuls sensorials i que són considerats ...