Ciampi, Ludovica (Date of defense: 2023-04-27)
The nervous system comprises an immense number of cells that serve highly specialized roles. Accordingly, they possess unique morphological and functional attributes, greatly shaped by specific Alternative ...
Martínez Navarro, Miriam (Date of defense: 2019-01-18)
La alta variabilidad interindividual en las manifestaciones de dolor neuropático puede conducir a una respuesta diferencial de los pacientes a los tratamientos, y sugiere la idoneidad de terapias más ...
Alemany González, Maria (Date of defense: 2019-07-09)
Understanding the neural correlates of intellectual disability is still a central and unresolved problem in neuroscience. Here we have unravelled several candidate neural substrates of memory impairment ...
Lara Mayorga, Itzel Montserrat (Date of defense: 2017-07-12)
Neuropathic pain is a complex disorder that includes nociceptive, emotional and cognitive manifestations. This work was focused on how inter-individual variability and endogenous opioid system may be ...
Ortiz Teba, Pilar (Date of defense: 2023-07-05)
Depression is a major public health problem, affecting 322 million people worldwide. Antidepressants are the basis for the treatment of major depression. Although increasingly safer, individual patient ...
Ortiz Romero, Paula (Date of defense: 2019-11-18)
Williams-Beuren syndrome (WBS) is a rare neurodevelopmental disorder caused by a heterozygous deletion of ~1.5 Mb in chromosome region 7q11.23. The use of murine models of the disease has helped to ...
Schulze, Aljoscha (Date of defense: 2015-09-18)
Animals have to deal with an environment presenting vast amounts of ever-changing sensory information. What features of this information flow are captured by the sensory system? My thesis work examines ...
Tornador Antolin, Cristian (Date of defense: 2016-01-25)
Depression is the most common type of emotional disorder among the world's population. It is characterized by negative sentiments, the feeling of guilt, low self-esteem, a loss of interest, a high-level ...
Morales, Hernán G. (Date of defense: 2012-09-28)
Nowadays, most popular therapies for cerebral aneurysms are clipping and coiling. Nonetheless, it is not easy to elucidate which therapeutic option is the most suitable and reliable for a patient-specific ...
Guivernau Almazán, Biuse (Date of defense: 2016-06-10)
Aggregation of the amyloid-β (Aβ) peptide to form oligomers and amyloid fibrils is a central event in the pathogenesis of Alzheimer’s disease (AD). This thesis aims to provide a better understanding of ...