Condemi, Livia (Date of defense: 2024-03-07)
Polycomb repressive complex (PRC) 2 is one of the key regulators of the transcriptional programs, it maintains stem cell properties and guides cell lineage specification. It is a multiprotein complex ...
Martin, Olivier M. F. (Date of defense: 2022-04-05)
Gràcies als amplis esforços d'investigació, la nostra comprensió dels mecanismes fisiològics de l'envelliment ha progressat enormement. Recentment, les tecnologies òmiques han permès l'estudi a tot el ...
Hong, Xiaotong (Date of defense: 2022-10-06)
La regeneración del músculo esquelético depende de la expansión correcta de las células madre inactivas residentes (células satélite), un proceso que se vuelve menos eficiente con el envejecimiento, por ...
Poliński, Patrik (Date of defense: 2022-04-07)
Microexons are an unusual form of alternative splicing with high evolutionary conservation, however, their functions are still far from being understood. In this thesis, we focused on a neuronal-specific ...
Bigorra López, Laura (Date of defense: 2022-04-08)
The complete blood count (CBC) is one of the most commonly performed test due to its clinical utility, versatility and safety. Thus, there are well established consensus rules to review a CBC through ...
Figueras Puig, Cristina (Date of defense: 2022-04-08)
Metastasis is the major cause of death from Breast Cancer (BCa). During its progression, divergent opinions have arisen regarding the hormonal status of the BCa subtypes. The mammary gland is composed ...
Mogas Diez, Sira (Date of defense: 2022-01-28)
This PhD thesis explores the potential embedded in living organisms, understood as highly complex machines which can sense, compute, and react to changes in their surroundings. From this general idea, ...
Domínguez Rodríguez, Diana (Date of defense: 2021-05-04)
La metàstasis és responsable del 90% de les morts per càncer, demostrant l’existent manca de coneixement en relació als seus mecanismes moleculars. Investigacions anteriors del nostre laboratori han ...
Vineethakumari Muraleedharan, Chithran (Date of defense: 2024-03-14)
Microtubules form diverse arrays according to the cell type or the cell cycle stage to facilitate the context-specific functions of the cytoskeleton. One way by which cells achieve this is by restricting ...
Ivancic, Dimitrie (Date of defense: 2024-04-03)
Methods for genome engineering have enabled construction of synthetic genomes, therapeutically reprogrammed cells, synthetic organs, and modification of human genomes. Design and discovery of genome ...